4-Amino-2,3-dihydroisoindol-1-one

Product Overview

4-Amino-2,3-dihydroisoindol-1-one is a high-value heterocyclic organic compound widely utilized as a critical building block in modern pharmaceutical manufacturing. With the CAS registry number 366452-98-4, this molecule serves as an essential intermediate in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the production of immunomodulatory agents such as lenalidomide derivatives. Our product is manufactured under stringent quality control protocols to ensure exceptional chemical integrity and batch-to-batch consistency, meeting the demanding standards of global pharmaceutical R&D and commercial-scale production.

Specifications

Industrial Applications

This compound is primarily employed as a specialized intermediate in multi-step synthetic routes targeting advanced neurological and oncological therapeutics. Its unique fused-ring structure with both amine and lactam functionalities enables versatile reactivity, making it ideal for constructing isoindolinone-based pharmacophores. Key application areas include:

• Synthesis of next-generation immunomodulatory drugs (IMiDs)
• Development of proteolysis-targeting chimeras (PROTACs)
• Building block for kinase inhibitors and epigenetic modulators
• Research applications in medicinal chemistry and drug discovery programs

Due to its role in regulated pharmaceutical pathways, this intermediate is strictly supplied for legitimate industrial and research purposes in compliance with international chemical safety and export regulations.

Handling and Storage

Store in a cool, dry, and well-ventilated area away from direct sunlight, heat sources, and incompatible materials. Keep container tightly sealed when not in use. Standard laboratory personal protective equipment (PPE) including gloves, goggles, and lab coat should be worn during handling. For detailed safety information, refer to the Safety Data Sheet (SDS) provided upon request.