4-Amino-2,6-dimethoxypyrimidine
- CAS No.3289-50-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Amino-2,6-dimethoxypyrimidine (CAS 3289-50-7), a key pharmaceutical intermediate in the synthesis of sulfonamide antibiotics such as Sulphadimethoxine.
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Product Overview
4-Amino-2,6-dimethoxypyrimidine is a high-value heterocyclic organic compound widely employed as a critical building block in the pharmaceutical industry. With the CAS registry number 3289-50-7, this molecule serves as an essential intermediate in the synthesis of sulfonamide-class antimicrobial agents, particularly Sulphadimethoxine. Its well-defined reactivity and structural features make it indispensable for constructing complex pyrimidine-based active pharmaceutical ingredients (APIs).
Specifications
| Molecular Formula | C6H9N3O2 |
|---|---|
| Molecular Weight | 155.15 g/mol |
| EINECS Number | 221-946-2 |
| Density | 1.2 ± 0.1 g/cm³ |
| Boiling Point | 340.1 ± 45.0 °C at 760 mmHg |
| Melting Point | 149–152 °C (lit.) |
| Flash Point | 159.5 ± 28.7 °C |
| Refractive Index | 1.547 |
| Appearance | White crystal |
| Assay | ≥95% |
| Residue on Ignition | ≤0.2% |
| Water Content | ≤0.5% |
Industrial Applications
This compound is primarily utilized as a synthetic intermediate in the production of Sulphadimethoxine, a long-acting sulfonamide antibiotic used in veterinary and human medicine. Its role in facilitating selective functionalization of the pyrimidine core enables efficient, scalable routes to target APIs under GMP-compliant conditions.
- Serves as a foundational scaffold for sulfonamide antibiotic synthesis
- Compatible with standard amidation and nucleophilic substitution protocols
- Supplied in industrial-grade purity suitable for multi-step pharmaceutical manufacturing
Handling and Storage
Store in a cool, well-ventilated warehouse away from heat sources and open flames. Maintain storage temperature below 37 °C. Packaging is typically provided in 25 kg drums, with custom options available upon request to meet specific logistical or regulatory requirements.
