4-Amino-2-fluorobenzoic Acid
- CAS No.446-31-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 4-Amino-2-fluorobenzoic Acid (CAS 446-31-1) suitable for pharmaceutical synthesis. Available in bulk quantities with comprehensive quality documentation.
Request Bulk PricingProduct Technical Details
Product Overview
4-Amino-2-fluorobenzoic Acid is a highly specialized fluorinated intermediate designed for advanced organic synthesis and pharmaceutical development. As a key building block in medicinal chemistry, this compound features a unique substitution pattern that enhances reactivity and stability in various chemical transformations. Our manufacturing process ensures consistent quality and high purity levels, making it an essential component for researchers and industrial producers alike.
The presence of the fluorine atom at the ortho position significantly influences the electronic properties of the benzene ring, facilitating specific coupling reactions and nucleophilic substitutions. This chemical is widely recognized for its utility in the construction of complex molecular architectures required in modern drug discovery pipelines.
Key Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 446-31-1 |
| Molecular Formula | C7H6FNO2 |
| Molecular Weight | 155.13 g/mol |
| Appearance | White-yellow crystalline powder |
| Purity (GC) | ≥99.0% |
| Melting Point | 210°C |
| Density | 1.43 g/cm³ |
| Boiling Point | 336.1°C |
Industrial Applications
This fluorinated benzoic acid derivative serves as a critical intermediate in the synthesis of various pharmaceutical agents and agrochemicals. Its primary application lies in the formation of heterocyclic compounds and biaryl structures through palladium-catalyzed cross-coupling reactions. The compound is particularly valued in the development of kinase inhibitors and other targeted therapies where fluorine substitution improves metabolic stability and bioavailability.
Beyond pharmaceuticals, 4-Amino-2-fluorobenzoic Acid is utilized in the production of high-performance polymers and liquid crystal materials. The robust chemical stability allows it to withstand harsh reaction conditions, ensuring high yields in multi-step synthesis routes. Our clients leverage this material for scaling up processes from laboratory research to commercial manufacturing.
Quality and Safety
We adhere to strict quality control protocols to guarantee the integrity of every batch. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity profiles and impurity limits. Proper storage in a cool, ventilated area is recommended to maintain stability over extended periods. Our team provides technical support to assist with handling guidelines and regulatory compliance documentation.
- Consistent batch-to-batch reproducibility
- Comprehensive impurity profiling available
- Flexible packaging options for bulk orders
- Global shipping with secure containment
