Intermediates

4-Amino-2-Fluorobenzotrifluoride

  • CAS No.69411-68-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Amino-2-Fluorobenzotrifluoride (CAS 69411-68-3) designed for advanced pharmaceutical synthesis. Reliable supply with ≥98.0% purity for global research and production needs.

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Product Technical Details

Product Overview

4-Amino-2-Fluorobenzotrifluoride is a highly specialized fluorinated aromatic compound serving as a critical building block in modern organic synthesis. Characterized by its unique substitution pattern featuring both amino and trifluoromethyl groups on the benzene ring, this chemical entity offers exceptional reactivity for constructing complex molecular architectures. Our facility produces this intermediate under strict quality control protocols to ensure consistency across batches, making it an ideal choice for pharmaceutical research and development teams.

The introduction of fluorine atoms into organic molecules is a cornerstone strategy in medicinal chemistry to enhance metabolic stability and bioavailability. This specific derivative provides a versatile platform for further functionalization, allowing chemists to develop novel therapeutic agents with improved pharmacokinetic profiles. We are committed to supplying this material with the highest standards of purity and documentation.

Technical Specifications

ParameterSpecification
Chemical Name4-Amino-2-Fluorobenzotrifluoride
CAS Number69411-68-3
Molecular FormulaC7H5F4N
Molecular Weight179.12 g/mol
Purity≥98.0%
AppearanceWhite powder
Melting Point55°C
Boiling Point203.8°C at 760 mmHg
Density1.383 g/cm3

Industrial Applications

This compound is primarily utilized as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its structural properties make it suitable for coupling reactions, nucleophilic substitutions, and heterocycle formations. In the pharmaceutical sector, it serves as a precursor for developing drugs targeting various therapeutic areas including oncology and central nervous system disorders. The presence of the trifluoromethyl group often imparts desirable lipophilicity and resistance to oxidative metabolism.

Beyond medicine, this chemical finds application in the creation of advanced materials and specialty polymers. Researchers value its stability and reactivity balance, which facilitates efficient scale-up from laboratory bench to industrial production. Our supply chain is optimized to support both small-scale research projects and large-scale manufacturing requirements.

Quality Assurance and Advantages

  • Consistent high purity levels exceeding 98.0% for reliable reaction outcomes.
  • Comprehensive quality documentation including Certificate of Analysis (COA).
  • Stable supply chain ensuring timely delivery for global clients.
  • Produced in compliance with international safety and environmental standards.
  • Technical support available for process optimization and application guidance.

Storage and Handling

To maintain product integrity, 4-Amino-2-Fluorobenzotrifluoride should be stored in a tightly closed container within a cool, dry, and well-ventilated area. Protection from moisture and direct sunlight is essential to prevent degradation. Standard laboratory safety practices should be followed during handling, including the use of appropriate personal protective equipment. We recommend consulting the safety data sheet for detailed hazard information and emergency procedures before use.