4-Amino-2-(trifluoromethyl)benzoic acid
- CAS No.393-06-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Amino-2-(trifluoromethyl)benzoic acid (CAS 393-06-6) for advanced organic synthesis. Available in bulk with strict quality control.
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Product Overview
4-Amino-2-(trifluoromethyl)benzoic acid is a specialized fluorinated organic compound widely recognized for its utility in modern medicinal chemistry and agrochemical development. As a key building block, this substance features a benzoic acid backbone substituted with an amino group and a trifluoromethyl moiety. The presence of the trifluoromethyl group significantly enhances the lipophilicity and metabolic stability of downstream molecules, making it an invaluable precursor in the design of high-performance pharmaceutical agents.
Our manufacturing process ensures consistent quality and high purity levels suitable for demanding research and industrial applications. This compound serves as a critical intermediate in the synthesis of various biologically active structures, including kinase inhibitors and novel herbicides. We adhere to strict production standards to guarantee that every batch meets the rigorous specifications required by global pharmaceutical and chemical industries.
Key Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 4-Amino-2-(trifluoromethyl)benzoic acid |
| CAS Number | 393-06-6 |
| Molecular Formula | C8H6F3NO2 |
| Molecular Weight | 205.134 g/mol |
| Appearance | Light yellow crystalline powder |
| Assay (Purity) | ≥98.0% |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 318.8±42.0 °C at 760 mmHg |
| Flash Point | 146.6±27.9 °C |
| Refractive Index | 1.528 |
Industrial Applications
In the pharmaceutical sector, this fluorinated benzoic acid derivative is extensively used to introduce trifluoromethyl groups into complex drug candidates. The electron-withdrawing nature of the trifluoromethyl group modulates the electronic properties of the aromatic ring, influencing binding affinity and selectivity towards biological targets. It is particularly relevant in the development of anti-inflammatory drugs, anticancer agents, and central nervous system therapeutics where metabolic stability is paramount.
Beyond pharmaceuticals, this compound finds application in agrochemical synthesis. It acts as a versatile intermediate for producing advanced herbicides and fungicides that require robust chemical stability under field conditions. The high purity provided by our manufacturing process ensures minimal side reactions during subsequent coupling or substitution steps, thereby improving overall yield and efficiency in multi-step synthesis routes.
Quality Assurance and Packaging
We maintain a comprehensive quality management system to ensure product integrity from synthesis to delivery. Each batch undergoes rigorous testing using advanced analytical techniques such as HPLC and NMR to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment to document compliance with specified standards.
- Packaging: Standard 25 kg drums, with custom packaging options available upon request.
- Storage: Store in a cool, ventilated place away from direct sunlight and moisture.
- Safety: Handle with appropriate personal protective equipment in accordance with safety data sheets.
- Shipping: Global logistics support ensuring timely and secure delivery to international destinations.
Our commitment to excellence makes us a reliable partner for sourcing high-quality chemical intermediates. Contact our technical team for detailed specifications, bulk pricing, or custom synthesis inquiries tailored to your specific project requirements.
