4-Amino-2-(trifluoromethyl)benzonitrile
- CAS No.654-70-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate designed for advanced organic synthesis. Available in bulk quantities with comprehensive quality documentation.
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Product Overview
4-Amino-2-(trifluoromethyl)benzonitrile is a specialized chemical intermediate widely utilized in the pharmaceutical and fine chemical industries. Characterized by its stable aromatic structure and reactive functional groups, this compound serves as a critical building block for complex molecular synthesis. The presence of the trifluoromethyl group enhances metabolic stability and lipophilicity in downstream products, making it highly valued in modern medicinal chemistry research and development.
Our manufacturing facility adheres to strict quality management systems to ensure consistent batch-to-batch reliability. We understand that precision in chemical composition is paramount for successful reaction outcomes. Therefore, every production lot undergoes rigorous analytical testing to verify identity, purity, and impurity profiles before release.
Key Specifications
The following table outlines the standard technical parameters and typical analysis results for this product. Our quality control team ensures that all shipments meet or exceed these specifications.
| Items of Analysis | Standard of Analysis | Test Results |
|---|---|---|
| Appearance | White or off-white powder | White powder |
| Melting point | 140.0-145.0℃ | 142.5-143.8℃ |
| Purity (HPLC) | ≥99.5% | 99.81% |
| Total impurity | ≤0.5% | 0.19% |
| The largest single impurity | ≤0.2% | 0.17% |
| Water | ≤0.5% | 0.15% |
| Conclusion | Conforms to Factory Standard | |
Quality Assurance And Handling
Maintaining the integrity of chemical intermediates during storage and transport is essential for preserving reactivity. Our quality assurance protocol includes comprehensive screening for residual solvents, heavy metals, and organic impurities. We utilize high-performance liquid chromatography (HPLC) to quantify purity levels with high precision.
- Strict control over reaction conditions to minimize by-product formation.
- Advanced purification techniques to achieve high purity levels.
- Comprehensive documentation including Certificate of Analysis (COA) for every batch.
- Regular stability testing to ensure shelf-life reliability.
Industrial Applications
This compound is primarily employed as a key precursor in the synthesis of various pharmaceutical agents and agrochemicals. Its structural features allow for versatile functionalization, enabling chemists to construct complex heterocyclic systems. It is particularly useful in processes requiring nucleophilic substitution or reduction reactions involving the nitrile or amino groups.
Researchers value this material for its consistent performance in scale-up processes. Whether used in laboratory-scale discovery or industrial-scale production, the material provides reliable reaction kinetics and yield profiles.
Packaging And Storage
To prevent degradation from moisture or light exposure, we offer specialized packaging solutions tailored to order volume. Small quantities are sealed in aluminum foil bags to ensure an airtight environment. Larger bulk orders are packaged in fiber drums lined with protective materials to maintain stability during international shipping.
Storage recommendations include keeping the container tightly closed in a cool, dry, and well-ventilated area. Avoid exposure to direct sunlight or strong oxidizing agents. Proper handling procedures should be followed in accordance with local safety regulations and material safety data sheets.
