Intermediates

4-Amino-3-chlorophenol

  • CAS No.17609-80-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 4-Amino-3-chlorophenol (CAS 17609-80-2) designed for pharmaceutical synthesis. Reliable supply for kinase inhibitor production with full documentation.

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Product Technical Details

Product Overview

4-Amino-3-chlorophenol is a specialized organic compound widely recognized for its critical role in medicinal chemistry and pharmaceutical manufacturing. As a key building block, this chemical serves as an essential intermediate in the synthesis of various advanced therapeutic agents. Our facility produces this compound under strict quality control standards to ensure consistency and reliability for downstream processing. The substance is characterized by its specific structural configuration, which allows for precise chemical modifications required in complex drug synthesis pathways.

We understand the demanding requirements of modern pharmaceutical research and production. Therefore, our manufacturing process focuses on achieving high purity levels while maintaining cost-effectiveness for bulk industrial applications. This product is particularly valued in the development of kinase inhibitors, where structural integrity and purity are paramount for efficacy and safety in final drug products.

Technical Specifications

To support our partners in quality assurance and regulatory compliance, we provide comprehensive technical data for every batch. The following table outlines the standard physical and chemical properties associated with this material. Please note that specific parameters may vary slightly based on production batches, and a Certificate of Analysis is available upon request.

ParameterSpecification
CAS Number17609-80-2
Molecular FormulaC6H6ClNO
Molecular Weight143.57 g/mol
AppearanceLight brown to dark solid
Purity≥98.0%
Density1.406 g/cm3
Boiling Point287.3 °C
Flash Point127.6 °C
Refractive Index1.606

Industrial Applications

The primary application of 4-Amino-3-chlorophenol lies within the pharmaceutical sector, specifically as a precursor for active pharmaceutical ingredients. It is extensively used in the synthesis pathways of targeted therapies such as Lenvatinib and Tivozanib. These compounds are vital in oncology research and treatment, highlighting the importance of high-quality intermediates in the supply chain. Chemical researchers utilize this building block for its reactivity and compatibility with various synthetic routes.

Beyond specific drug synthesis, this chemical finds utility in broader organic synthesis projects where chlorinated aminophenol structures are required. Our team supports custom synthesis requests to meet unique research needs, ensuring that specific purity profiles or packaging requirements are met. We work closely with process chemists to optimize the integration of this material into larger manufacturing workflows.

Quality Assurance and Safety

Quality is the cornerstone of our operation. Every production batch undergoes rigorous testing using advanced analytical techniques such as HPLC and NMR to verify identity and purity. We adhere to international safety standards and provide comprehensive documentation including MSDS and COA with every shipment. This ensures that our clients can maintain their own quality systems without interruption.

Proper storage and handling are essential for maintaining product stability. We recommend storing the material in a cool, ventilated area away from direct sunlight and moisture. Packaging is available in standard 25 kg drums, with flexible options to suit logistical requirements. Our global logistics network ensures timely delivery while maintaining the integrity of the chemical during transit. For further technical support or procurement inquiries, our sales team is ready to assist with competitive bulk pricing and detailed product information.