4-Amino-3-fluorophenol
- CAS No.399-95-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Amino-3-fluorophenol (CAS 399-95-1) designed for pharmaceutical synthesis. Reliable bulk supply with strict quality control.
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Product Overview
4-Amino-3-fluorophenol is a specialized fluorinated organic compound widely recognized for its critical role in modern medicinal chemistry and pharmaceutical manufacturing. As a key building block, this chemical intermediate facilitates the synthesis of complex therapeutic agents, including kinase inhibitors used in oncology research. Our facility produces this compound under stringent quality management systems to ensure consistency and reliability for downstream processing.
The introduction of a fluorine atom at the meta position relative to the hydroxyl group significantly enhances the metabolic stability and binding affinity of final drug molecules. This makes 4-Amino-3-fluorophenol an invaluable asset for research laboratories and industrial production lines focused on developing advanced neurological therapeutics and complex pharmaceutical APIs. We commit to delivering material that meets or exceeds international standards for purity and performance.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 4-Amino-3-fluorophenol |
| CAS Number | 399-95-1 |
| Molecular Formula | C6H6FNO |
| Molecular Weight | 127.116 |
| Appearance | Dark brown solid |
| Assay | ≥98.0% |
| Melting Point | 135-137°C |
| Boiling Point | 270.4±25.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 117.3±23.2 °C |
Quality Assurance And Manufacturing
Our production process employs advanced organic synthesis techniques to maximize yield while minimizing impurities. Each batch undergoes rigorous analytical testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy. We maintain full traceability from raw material sourcing to final packaging, ensuring that every drum meets the specified assay requirements.
- Strict control over reaction conditions to ensure structural integrity.
- Comprehensive impurity profiling to support regulatory filings.
- Batch-specific certificates of analysis (COA) provided with every shipment.
- Manufactured in compliance with ISO quality management standards.
- Regular third-party auditing to verify production capabilities.
Applications And Usage
This intermediate is primarily utilized in the multistep synthesis of targeted therapeutic compounds. It serves as a essential precursor in the manufacturing process of various small molecule drugs. Researchers value this material for its reactivity and stability during coupling reactions. While commonly associated with the synthesis of specific kinase inhibitors, its utility extends to broader applications in agrochemicals and material science where fluorinated aromatics are required.
Storage And Handling
To maintain optimal quality, 4-Amino-3-fluorophenol should be stored in a cool, ventilated place away from direct sunlight and moisture. The material is packaged in 25 kg drums, though custom packaging solutions are available to meet specific logistical requirements. Personnel handling this chemical should wear appropriate personal protective equipment, including gloves and safety goggles, to prevent skin contact or inhalation of dust. Proper ventilation is essential during transfer operations to ensure workplace safety.
We offer global shipping capabilities with secure packaging to prevent damage during transit. Our logistics team coordinates with freight forwarders to ensure timely delivery to ports worldwide. For large volume requirements, we provide competitive bulk pricing and dedicated account management to support your supply chain needs. Contact our technical sales team for detailed specifications and current availability.
