4-Amino-3-iodobenzotrifluoride
- CAS No.163444-17-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Amino-3-iodobenzotrifluoride (CAS 163444-17-5) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for pharmaceutical and agrochemical intermediate applications.
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Product Overview
4-Amino-3-iodobenzotrifluoride is a highly specialized fluorinated chemical intermediate engineered for complex organic synthesis pathways. As a critical building block in modern medicinal chemistry, this compound features a unique structural arrangement combining an amino group, an iodine substituent, and a trifluoromethyl group on a benzene ring. This specific configuration provides exceptional reactivity profiles, making it indispensable for researchers and industrial manufacturers focused on developing next-generation pharmaceutical agents and agrochemical solutions.
The incorporation of fluorine atoms into organic molecules is a strategic approach to enhance metabolic stability, lipophilicity, and bioavailability. Our grade of 4-Amino-3-iodobenzotrifluoride ensures that downstream synthesis processes benefit from consistent quality and high purity levels. We understand the rigorous demands of the fine chemical industry, which is why our production protocols adhere to strict quality management systems to guarantee batch-to-batch consistency.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 4-Amino-3-iodobenzotrifluoride |
| CAS Number | 163444-17-5 |
| Molecular Formula | C7H5F3IN |
| Molecular Weight | 287.021 g/mol |
| Appearance | White to off-white powder |
| Assay (Purity) | ≥98.0% |
| Melting Point | 50 °C |
| Boiling Point | 252.8±40.0 °C at 760 mmHg |
| Density | 1.9±0.1 g/cm3 |
| Flash Point | 106.7±27.3 °C |
Industrial Applications
This fluorinated intermediate serves as a versatile precursor in the synthesis of various high-value compounds. Its primary utility lies in the pharmaceutical sector, where it is utilized to construct active pharmaceutical ingredients (APIs) requiring enhanced pharmacokinetic properties. The presence of the iodine atom facilitates cross-coupling reactions, such as Suzuki or Heck couplings, enabling chemists to introduce diverse functional groups efficiently.
Beyond pharmaceuticals, this compound finds application in agrochemical development, where fluorinated structures often confer improved pesticidal activity and environmental stability. Researchers also leverage this material in the creation of advanced organic materials and liquid crystals. The high purity specification ensures minimal side reactions during synthesis, optimizing yield and reducing purification costs for large-scale manufacturing operations.
Quality Assurance and Safety
Quality is the cornerstone of our manufacturing philosophy. Every batch of 4-Amino-3-iodobenzotrifluoride undergoes rigorous analytical testing using advanced chromatography and spectroscopy methods. We provide a comprehensive Certificate of Analysis (COA) with every shipment, detailing purity levels and physical constants. Our facility operates under strict safety guidelines to ensure the product remains stable and uncontaminated throughout the production lifecycle.
For safe handling, this chemical should be stored in a cool, ventilated place away from incompatible substances. Proper personal protective equipment is recommended during handling to prevent exposure. We offer flexible packaging options, including standard 25 kg drums, and can customize packaging according to specific customer requirements to facilitate safe global logistics. Our commitment extends beyond the product itself, offering technical support to assist with integration into your specific synthesis routes.
