4-Amino-3-(trifluoromethoxy)benzoic acid
- CAS No.175278-22-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Amino-3-(trifluoromethoxy)benzoic acid (CAS 175278-22-5) designed for advanced organic synthesis and pharmaceutical intermediate applications.
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Product Overview
4-Amino-3-(trifluoromethoxy)benzoic acid is a specialized fluorinated organic compound serving as a critical building block in modern chemical synthesis. Characterized by the presence of both an amino group and a carboxylic acid moiety on a benzene ring substituted with a trifluoromethoxy group, this molecule offers unique reactivity profiles essential for constructing complex pharmaceutical architectures. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding research and industrial scale-up projects.
The introduction of the trifluoromethoxy group significantly enhances the lipophilicity and metabolic stability of downstream molecules, making this intermediate highly valued in medicinal chemistry. We provide this compound with rigorous quality control standards to support the development of novel therapeutic agents and advanced materials.
Key Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 4-Amino-3-(trifluoromethoxy)benzoic acid |
| CAS Number | 175278-22-5 |
| Molecular Formula | C8H6F3NO3 |
| Molecular Weight | 221.13 g/mol |
| Appearance | White solid |
| Purity | ≥99.0% |
| Melting Point | 168-169°C |
| Density | 1.528 g/cm³ |
Industrial Applications
This fluorinated benzoic acid derivative is primarily utilized as a versatile intermediate in the synthesis of pharmaceutical active ingredients. The amino group allows for various coupling reactions, including amide bond formation, while the carboxylic acid functionality enables esterification or further functionalization. Common applications include the development of kinase inhibitors, anti-inflammatory agents, and other small molecule drugs where fluorine substitution is required to optimize pharmacokinetic properties.
Beyond pharmaceuticals, this compound finds utility in agrochemical research and the creation of specialized organic materials. Its stability under various reaction conditions makes it a reliable choice for multi-step synthesis routes. Researchers value this intermediate for its ability to introduce specific electronic and steric effects into target molecules, facilitating the discovery of compounds with enhanced biological activity.
Quality Assurance and Storage
We adhere to strict quality management systems to ensure every batch meets the specified purity requirements. Each shipment is accompanied by a Certificate of Analysis (COA) detailing comprehensive testing results. Our production facilities employ advanced analytical techniques to verify identity and assess impurities, guaranteeing material consistency for our global partners.
For optimal stability, store this product in a cool, ventilated area away from direct sunlight and moisture. Keep containers tightly closed when not in use to prevent degradation. We offer flexible packaging options, including standard 25 kg drums, and can accommodate custom packaging requirements based on specific logistical needs. Our logistics team ensures safe and compliant global delivery.
