Intermediates

4-Amino-N-Boc-L-Phenylalanine

  • CAS No.55533-24-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Amino-N-Boc-L-Phenylalanine (CAS 55533-24-9) designed for pharmaceutical synthesis. Reliable supply for Melphalan intermediate production with strict quality control.

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Product Technical Details

Product Overview

Our premium 4-Amino-N-Boc-L-Phenylalanine is a specialized amino acid derivative engineered for high-performance pharmaceutical synthesis. As a critical building block in modern medicinal chemistry, this compound features a tert-butoxycarbonyl (Boc) protecting group on the alpha-amino function, ensuring stability during complex coupling reactions. We maintain rigorous production standards to deliver consistent quality suitable for large-scale API manufacturing and research applications.

This compound serves as a vital precursor in the synthesis of various therapeutic agents, including alkylating agents used in oncology. The strategic protection of the amino group allows chemists to perform selective reactions on the carboxylic acid or the aromatic amine without compromising the stereochemical integrity of the L-phenylalanine backbone. Our manufacturing process emphasizes optical purity and chemical homogeneity to support downstream processing efficiency.

Technical Specifications

We adhere to strict internal quality control protocols that exceed standard industry expectations. Each batch undergoes comprehensive analytical testing to verify identity, purity, and physical properties. The following table outlines the key technical parameters for this product:

ParameterSpecification
CAS Number55533-24-9
Molecular FormulaC14H20N2O4
Molecular Weight280.32 g/mol
AppearanceWhite to off-white powder
Assay (HPLC)≥98.0%
Density1.2±0.1 g/cm3
Boiling Point484.9±40.0 °C at 760 mmHg
Flash Point247.0±27.3 °C

Quality Assurance and Storage

Quality assurance is the cornerstone of our operation. We utilize advanced chromatography and spectroscopy techniques, including HPLC and NMR, to confirm the structural integrity and purity of every lot. Certificate of Analysis (COA) documents are provided with each shipment, ensuring full traceability and compliance with your internal quality systems. Our facility operates under guidelines that prioritize safety and environmental responsibility.

To maintain optimal stability, 4-Amino-N-Boc-L-Phenylalanine should be stored in a cool, ventilated environment away from direct sunlight and moisture. The Boc group is sensitive to strong acids, so proper handling procedures are recommended during synthesis. We offer flexible packaging options, including 25 kg drums, and can accommodate custom packaging requirements to suit your logistical needs. Our global supply chain ensures timely delivery to support your production schedules.

Industrial Applications

This intermediate is primarily utilized in the pharmaceutical industry for the synthesis of complex active pharmaceutical ingredients (APIs). A notable application includes its role as a key intermediate in the production of Melphalan, a chemotherapy medication. Beyond oncology, Boc-protected amino acids are fundamental in peptide synthesis, combinatorial chemistry, and the development of novel therapeutic candidates. Our commitment to providing high-purity materials supports innovation in drug discovery and development.

  • Optimized for scalable pharmaceutical manufacturing processes.
  • Ensures high yield and minimal byproduct formation in coupling reactions.
  • Supported by technical expertise for process optimization.
  • Available in bulk quantities for industrial clients.