Intermediates

4-Aminobenzonitrile

  • CAS No.873-74-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Aminobenzonitrile (CAS 873-74-5) designed for pharmaceutical synthesis. Reliable supply with strict quality control for API manufacturing.

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Product Technical Details

Product Overview

4-Aminobenzonitrile is a critical organic intermediate widely utilized in the synthesis of complex pharmaceutical compounds. Characterized by its dual functional groups, the amine and nitrile moieties offer versatile reactivity for various chemical transformations. Our manufacturing facility produces this compound under stringent quality management systems to ensure consistency and reliability for downstream applications. This product serves as a foundational building block in the development of advanced therapeutic agents, particularly within the antiretroviral sector.

We understand the importance of supply chain stability in the pharmaceutical industry. As a dedicated manufacturer, we provide bulk quantities with guaranteed specifications to support large-scale production needs. Our commitment to excellence extends from raw material sourcing to final packaging, ensuring that every drum meets the highest industry standards for purity and safety.

Technical Specifications

Quality control is paramount in the production of fine chemical intermediates. The following table outlines the key physical and chemical properties verified through our internal laboratory testing protocols. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) to validate compliance with specified parameters.

Parameter Specification
CAS Number 873-74-5
Molecular Formula C7H6N2
Molecular Weight 118.14 g/mol
Appearance White to light yellow crystalline powder
Assay (Purity) ≥99.0%
Melting Point 83-87 °C
Total Impurities ≤0.5%
Ash Content ≤0.2%

Industrial Applications

The primary application of 4-Aminobenzonitrile lies in the synthesis of active pharmaceutical ingredients (APIs). It is notably recognized as a key intermediate in the manufacturing process of Rilpivirine, a non-nucleoside reverse transcriptase inhibitor used in antiretroviral therapy. The high purity of our product minimizes side reactions during synthesis, thereby improving overall yield and reducing purification costs for our clients.

Beyond pharmaceuticals, this chemical finds utility in the production of agrochemicals and specialized dyes. The nitrile group allows for further functionalization into carboxylic acids, amines, or tetrazoles, making it a versatile component in organic synthesis routes. Researchers and process chemists value this intermediate for its stability and predictable reactivity profiles under standard laboratory conditions.

Quality Assurance and Storage

To maintain product integrity, we employ advanced analytical techniques including HPLC and GC-MS to monitor impurity profiles such as 2-aminobenzonitrile and 3-aminobenzonitrile isomers. Our quality assurance team ensures that the sum of these isomers remains below 0.5%, adhering to strict regulatory guidelines for pharmaceutical intermediates.

Proper storage is essential to preserve the chemical properties of 4-Aminobenzonitrile. The product should be stored in a cool, ventilated area away from direct sunlight and moisture. We offer flexible packaging options, typically supplying in 25 kg drums, but can accommodate custom packaging requirements based on specific logistical needs. Our global distribution network ensures timely delivery while maintaining compliance with international shipping regulations for chemical substances.