4-Aminopyrazolo[3,4-d]pyrimidine
- CAS No.2380-63-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Aminopyrazolo[3,4-d]pyrimidine (CAS 2380-63-4) designed for pharmaceutical synthesis. Ideal intermediate for Ibrutinib production with ≥98.0% assay guarantee.
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Product Overview
4-Aminopyrazolo[3,4-d]pyrimidine is a highly specialized heterocyclic compound that plays a pivotal role in modern medicinal chemistry and pharmaceutical manufacturing. As a critical building block, this chemical entity is extensively utilized in the synthesis of kinase inhibitors and other advanced therapeutic agents. Our facility specializes in the production of this intermediate with a focus on maintaining exceptional purity levels and consistent quality standards required by the global pharmaceutical industry.
The molecular structure of this compound features a fused pyrazolo and pyrimidine ring system, which provides unique chemical reactivity suitable for complex organic synthesis pathways. We understand the stringent requirements of drug development pipelines, which is why our manufacturing processes are optimized to deliver material that meets or exceeds international pharmacopoeia standards for intermediates.
Key Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 2380-63-4 |
| Molecular Formula | C5H5N5 |
| Molecular Weight | 193.671 g/mol |
| Appearance | Beige to brown powder |
| Assay (HPLC) | ≥98.0% |
| Loss on Drying | ≤1.0% |
| Melting Point | >325 °C |
| Density | 1.612 g/cm3 |
Industrial Applications
This product serves primarily as a key intermediate in the manufacturing of Ibrutinib, a prominent pharmaceutical agent used in the treatment of certain malignancies. The high purity of our 4-Aminopyrazolo[3,4-d]pyrimidine ensures efficient downstream reactions, minimizing impurity profiles in the final active pharmaceutical ingredient (API). Beyond this specific application, the compound is valuable for research and development activities focused on novel purine analogs and nucleoside therapies.
- Essential building block for kinase inhibitor synthesis
- Compatible with various coupling and substitution reactions
- Supports scalable production for commercial drug manufacturing
- Utilized in academic and industrial research for heterocyclic chemistry
Quality Assurance And Storage
Quality control is paramount in our operations. Every batch of 4-Aminopyrazolo[3,4-d]pyrimidine undergoes rigorous testing using high-performance liquid chromatography (HPLC) to verify assay purity and identify any potential contaminants. We provide a comprehensive Certificate of Analysis (COA) with every shipment to ensure full transparency and compliance with your quality protocols.
The material is packaged in secure 25 kg drums, designed to protect the product from moisture and environmental contaminants during transit. Custom packaging solutions are available upon request to suit specific logistical needs. For optimal stability, we recommend storing the chemical in a cool, ventilated area away from direct sunlight and incompatible substances. Our global supply chain ensures timely delivery to support your continuous manufacturing schedules without interruption.
