Intermediates

4-Biphenylboronic acid

  • CAS No.5122-94-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Biphenylboronic acid (CAS 5122-94-1) designed for pharmaceutical synthesis and biaryl compound preparation. Available in bulk quantities with strict quality control.

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Product Technical Details

Product Overview

4-Biphenylboronic acid is a highly valued organoboron compound widely recognized for its critical role in modern organic synthesis and medicinal chemistry. As a stable boronic acid derivative, it serves as an essential building block for constructing complex biaryl structures through palladium-catalyzed cross-coupling reactions. Our facility produces this intermediate under stringent quality management systems to ensure consistent performance in downstream applications.

This chemical entity is particularly favored in the pharmaceutical industry for the development of active pharmaceutical ingredients (APIs). Its robust chemical stability and high reactivity make it an ideal candidate for Suzuki-Miyaura coupling processes, enabling chemists to efficiently form carbon-carbon bonds. We commit to supplying materials that meet or exceed international standards for purity and safety.

Technical Specifications

Our production process emphasizes precision and reproducibility. Each batch undergoes rigorous analytical testing to verify compliance with specified parameters. The following table outlines the key physical and chemical properties of our standard grade product.

ParameterSpecification
Product Name4-Biphenylboronic acid
CAS Number5122-94-1
Molecular FormulaC12H11BO2
Molecular Weight198.03 g/mol
AppearanceWhite powder
Assay (Purity)Greater than or equal to 98.0 percent
Water ContentLess than or equal to 0.50 percent
Melting Point232-245 degrees Celsius
Density1.18 g/cm3

Industrial Applications

The primary utility of 4-Biphenylboronic acid lies in its function as a versatile intermediate for synthesizing biaryl compounds. These structures are foundational motifs in numerous therapeutic agents, including anti-inflammatory drugs, kinase inhibitors, and antiviral medications. Beyond pharmaceuticals, this compound finds application in material science for the creation of organic electronic materials and polymers.

Chemists utilize this reagent to introduce phenyl groups into complex molecular frameworks with high regioselectivity. Its compatibility with various functional groups allows for flexible synthetic routes without requiring extensive protection-deprotection strategies. This efficiency reduces overall production time and cost for research and development teams.

Quality Assurance and Safety

We maintain a comprehensive quality control protocol that includes raw material inspection, in-process monitoring, and final product verification. Certificates of Analysis (COA) are provided with every shipment to guarantee traceability and compliance. Our manufacturing plant adheres to safety regulations, ensuring that the product is classified as non-dangerous goods for transport under standard conditions.

  • Strict batch testing for purity and impurities
  • Stable supply chain for global distribution
  • Technical support available for synthesis optimization
  • Custom packaging solutions upon request

Packaging and Storage

To preserve integrity during transit, 4-Biphenylboronic acid is packaged in durable containers suitable for bulk industrial use. Standard packaging includes 25kg drums, though we accommodate specific customer requirements for larger or smaller quantities. Proper storage involves keeping the container tightly closed in a cool, dry, and well-ventilated area away from incompatible substances. Following these guidelines ensures the material retains its specified properties over extended periods.