Intermediates

4-Boc-4,7-diazaspiro[2.5]octane

  • CAS No.674792-08-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade 4-Boc-4,7-diazaspiro[2.5]octane intermediate for advanced organic synthesis. High purity guaranteed with comprehensive COA.

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Product Technical Details

Product Overview

4-Boc-4,7-diazaspiro[2.5]octane is a highly specialized organic intermediate characterized by its unique spirocyclic structure and Boc-protected amine functionality. This compound serves as a critical building block in the synthesis of complex pharmaceutical agents and advanced organic materials. The incorporation of the spiro[2.5]octane scaffold provides conformational rigidity, which is often desirable in medicinal chemistry to improve binding affinity and metabolic stability of drug candidates. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding research and development applications.

Technical Specifications

We adhere to strict quality control protocols to guarantee the physical and chemical properties of this intermediate. The compound is typically supplied as an off-white to light yellow solid, indicating high stability under standard storage conditions. The Boc protecting group offers robust stability against various reaction conditions while allowing for selective deprotection when required. Below are the detailed analytical specifications verified by our quality assurance team.

ParameterSpecificationTypical Result
AppearanceOff-white to light yellow solidConform
CAS Number674792-08-6674792-08-6
Molecular FormulaC11H20N2O2C11H20N2O2
Molecular Weight212.29 g/mol212.29 g/mol
Purity (GC)≥ 95.0%97.4%
Boiling Point301.3°C at 760 mmHg301.3°C
Density1.1 g/cm31.1 g/cm3

Industrial Applications

This spirocyclic diamine derivative is extensively utilized in the pharmaceutical industry for the construction of novel heterocyclic systems. The rigid spiro core helps in reducing the entropic penalty during receptor binding, making it a valuable motif in drug design. Additionally, it serves as a versatile precursor for generating diverse libraries of compounds in combinatorial chemistry. The protected amine functionality allows for further functionalization without compromising the integrity of the spiro cycle.

  • Used as a key intermediate in the synthesis of kinase inhibitors.
  • Employed in the development of GPCR modulators.
  • Utilized for creating conformationally constrained peptidomimetics.
  • Applied in organic synthesis for constructing complex polycyclic structures.

Quality Assurance

Our facility operates under rigorous quality management systems to ensure every batch meets international standards. Each shipment is accompanied by a Certificate of Analysis (COA) detailing the test results for purity, identity, and physical properties. We utilize advanced gas chromatography and spectroscopic methods to verify the structural integrity of the product. Customers can rely on our consistent supply chain and technical support for their synthesis projects.