4-Bromo-1,3-bis(trifluoromethyl)benzene
- CAS No.327-75-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Bromo-1,3-bis(trifluoromethyl)benzene (CAS 327-75-3) designed for advanced organic synthesis and pharmaceutical intermediates.
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Product Overview
4-Bromo-1,3-bis(trifluoromethyl)benzene represents a critical fluorinated aromatic intermediate within the realm of advanced organic synthesis. This specialized chemical compound is characterized by the strategic placement of a bromine atom alongside two trifluoromethyl groups on a benzene ring. The presence of trifluoromethyl moieties significantly enhances the metabolic stability and lipophilicity of downstream molecules, making this substance highly valuable in medicinal chemistry and agrochemical development. Our manufacturing process ensures consistent quality and reliability for research and industrial scale applications.
Key Specifications
| Parameter | Value |
|---|---|
| CAS Number | 327-75-3 |
| Molecular Formula | C8H3BrF6 |
| Molecular Weight | 293.004 |
| Appearance | Colorless to light yellow transparent liquid |
| Assay | ≥98.0% |
| Density | 1.7±0.1 g/cm3 |
| Boiling Point | 159.0±0.0 °C at 760 mmHg |
| Flash Point | 69.4±0.0 °C |
Industrial Applications
This fluorinated benzene derivative serves as a versatile building block for the construction of complex molecular architectures. In the pharmaceutical sector, it is utilized to introduce trifluoromethyl groups which are known to improve bioavailability and binding affinity in drug candidates. The bromine functionality allows for further functionalization through cross-coupling reactions such as Suzuki or Buchwald-Hartwig couplings. Additionally, this compound finds utility in the synthesis of high-performance materials and agrochemical agents where chemical stability and specific electronic properties are required. Its robust nature facilitates diverse synthetic routes for specialized chemical production.
Quality Assurance And Storage
We adhere to stringent quality control protocols to guarantee the integrity of every batch produced. Each shipment is accompanied by a comprehensive Certificate Of Analysis (COA) verifying purity and physical constants. Proper handling is essential to maintain product stability during transport and storage. We recommend storing this material in a cool, ventilated place away from direct sunlight and incompatible substances. Our packaging options are flexible to meet specific logistical requirements while ensuring safety compliance.
- Packaging: 25 kg/drum or customized according to customer requirements.
- Storage: Keep container tightly closed in a dry and well-ventilated area.
- Safety: Use appropriate personal protective equipment during handling.
- Support: Technical documentation and safety data sheets available upon request.
