Intermediates

4-Bromo-1-butene

  • CAS No.5162-44-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Bromo-1-butene (CAS 5162-44-7) designed for advanced organic synthesis applications. Available in bulk with comprehensive quality documentation.

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Product Technical Details

Product Overview

4-Bromo-1-butene is a specialized alkenyl halide that serves as a versatile building block in modern organic chemistry. Characterized by its dual functionality, this compound features both a terminal double bond and a reactive bromine substituent, making it an invaluable reagent for complex molecular constructions. Our facility produces this chemical under strict quality control protocols to ensure consistent performance in sensitive synthetic pathways. The material is supplied as a colorless transparent liquid, meeting rigorous industry standards for purity and stability.

As a leading global manufacturer, we understand the critical nature of raw material quality in pharmaceutical and agrochemical development. Each batch of 4-Bromo-1-butene undergoes comprehensive analytical testing to verify composition and eliminate impurities that could interfere with downstream reactions. This commitment to excellence ensures that research and production teams can rely on our products for reproducible results.

Key Specifications

ParameterSpecification
CAS Number5162-44-7
Molecular FormulaC4H7Br
Molecular Weight135.00 g/mol
Purity≥98.0%
AppearanceColorless transparent liquid
Density1.33 g/mL at 25 °C
Boiling Point98-100 °C
Refractive Index1.462

Industrial Applications

The primary utility of 4-Bromo-1-butene lies in its role as a synthetic intermediate for creating higher-order organic structures. The presence of the allylic bromide moiety allows for nucleophilic substitution reactions, while the alkene group facilitates addition reactions such as hydroboration or epoxidation. This dual reactivity profile makes it particularly useful in the synthesis of pharmaceutical intermediates, fine chemicals, and specialized polymers.

In medicinal chemistry, this compound is often employed to introduce four-carbon chains with terminal unsaturation into drug candidates. It serves as a precursor for various heterocyclic compounds and is frequently utilized in cross-coupling reactions. The high purity grade we provide ensures minimal side reactions, which is essential when working with expensive catalysts or sensitive biological targets. Researchers value this material for its reliability in scaling up from laboratory discovery to pilot production.

Storage and Handling

Proper storage is essential to maintain the integrity of 4-Bromo-1-butene. The product should be kept in a cool, dry, and well-ventilated warehouse environment. It is crucial to store containers away from strong oxidizing agents and acids to prevent hazardous reactions. The material is flammable, with a flash point of 49 °F, so appropriate fire safety measures must be in place. All containers should be kept tightly sealed when not in use to prevent moisture ingress and volatilization.

During transportation and handling, care must be taken to avoid physical damage to packaging. Drums should be stored in a vertical position to prevent leakage. We recommend using personal protective equipment, including chemical-resistant gloves and safety goggles, when handling this substance. Our packaging options include 25 kg drums, with custom configurations available to meet specific logistical requirements. By adhering to these guidelines, customers can ensure safe and effective use of this chemical intermediate in their operations.