4-Bromo-1-fluoro-2-nitrobenzene
- CAS No.364-73-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
Premium grade 4-Bromo-1-fluoro-2-nitrobenzene designed for complex organic synthesis pathways and pharmaceutical intermediate production.
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Product Overview
4-Bromo-1-fluoro-2-nitrobenzene represents a critical class of fluorinated aromatic compounds utilized extensively within the fine chemical and pharmaceutical sectors. As a versatile building block, this substance features a unique substitution pattern on the benzene ring, incorporating bromo, fluoro, and nitro functional groups. This specific arrangement enhances its reactivity towards nucleophilic aromatic substitution, making it an indispensable precursor for the development of advanced agrochemicals, pharmaceuticals, and specialized organic materials. Our facility maintains strict production standards to ensure consistent quality and reliability for large-scale industrial applications.
The molecular structure allows for selective transformations, enabling chemists to introduce diverse functional groups during downstream synthesis. Due to the presence of the fluorine atom, derivatives synthesized from this intermediate often exhibit improved metabolic stability and bioavailability, which are crucial parameters in modern drug discovery pipelines. We specialize in supplying this material with high purity levels to support rigorous research and development projects as well as commercial manufacturing processes.
Technical Specifications
Quality control is paramount in our manufacturing process. Each batch undergoes comprehensive analytical testing to verify compliance with international standards. The physical and chemical properties are meticulously monitored to ensure performance consistency in your synthesis routes. Below are the key specifications for our standard grade product:
| Parameter | Specification |
|---|---|
| Chemical Name | 4-Bromo-1-fluoro-2-nitrobenzene |
| CAS Number | 364-73-8 |
| Molecular Formula | C6H3BrFNO2 |
| Molecular Weight | 219.996 g/mol |
| Appearance | Light yellow liquid |
| Assay (Purity) | ≥98.0% |
| Density | 1.8±0.1 g/cm3 |
| Boiling Point | 257.5±20.0 °C at 760 mmHg |
| Melting Point | 18-19 °C |
| Flash Point | 109.5±21.8 °C |
Industrial Applications
This fluorinated nitrobenzene derivative serves as a foundational intermediate in various chemical synthesis pathways. Its primary utility lies in the construction of complex molecular architectures required for high-performance materials and active pharmaceutical ingredients. The reactivity of the nitro group allows for reduction to amines, while the bromo and fluoro substituents offer sites for cross-coupling reactions and nucleophilic substitutions respectively.
- Pharmaceutical Intermediate Synthesis: Used in the production of kinase inhibitors and other therapeutic agents.
- Agrochemical Development: Essential for creating novel herbicides and pesticides with enhanced environmental profiles.
- Organic Material Science: Employed in the synthesis of liquid crystals and polymer additives.
- Custom Chemical Manufacturing: Suitable for bespoke synthesis routes requiring high purity starting materials.
Quality Assurance and Logistics
We understand the importance of supply chain reliability in the chemical industry. Our production facilities are equipped with state-of-the-art technology to ensure industrial purity and batch-to-batch consistency. Every shipment is accompanied by a Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS) to facilitate safe handling and regulatory compliance. We offer flexible packaging solutions, including 200 kg drums, and can accommodate custom packaging requirements based on specific client needs. Storage recommendations include keeping the product in a cool, ventilated place away from incompatible substances to maintain stability over time. Contact our sales team for detailed information on bulk pricing and global shipping options.
