4-Bromo-1-methoxy-2-(3-methoxypropoxy)benzene

Product Overview

4-Bromo-1-methoxy-2-(3-methoxypropoxy)benzene is a specialized organic compound serving as a critical building block in the pharmaceutical industry. With the CAS registry number 173336-76-0, this chemical entity is primarily utilized in the multi-step synthesis of antihypertensive agents, specifically as a key intermediate for Aliskiren hemifumarate. Our facility produces this compound under stringent quality control protocols to ensure consistency and reliability for downstream API manufacturing.

The molecular structure, defined by the formula C11H15BrO3, features a brominated benzene ring substituted with methoxy and methoxypropoxy groups. This specific configuration is essential for the subsequent coupling reactions required in the production of renin inhibitors. We understand the critical nature of supply chain stability for pharmaceutical clients, which is why we maintain robust inventory levels and scalable production capabilities.

Technical Specifications

Quality is the cornerstone of our manufacturing process. Each batch undergoes rigorous analytical testing using HPLC, GC, and NMR spectroscopy to verify identity and purity. The following table outlines the standard specifications for our commercial grade material:

Quality Assurance and Manufacturing

Our production facility adheres to international quality management standards. We implement a comprehensive Quality Assurance (QA) system that covers raw material sourcing, in-process control, and final product release. Every shipment is accompanied by a Certificate of Analysis (COA) detailing the specific test results for that batch. This transparency allows our partners to validate the material against their internal standards without delay.

• Strict impurity profiling to ensure individual impurities remain below 0.2%.
• Advanced purification techniques to achieve high optical and chemical purity.
• Regular audits and compliance checks to maintain regulatory readiness.
• Dedicated support team for technical queries and documentation.

Industrial Applications

The primary application of this compound is in the synthesis of Aliskiren, a direct renin inhibitor used to treat essential hypertension. As a key intermediate, its quality directly impacts the yield and purity of the final Active Pharmaceutical Ingredient (API). Beyond this specific use, the chemical structure offers versatility for researchers exploring novel cardiovascular therapeutics or related organic synthesis pathways requiring brominated anisole derivatives.

Storage and Handling

To maintain stability and prevent degradation, proper storage conditions are essential. The product should be kept in a tightly sealed container within a cool, dry, and well-ventilated area. We recommend storage temperatures between 0-6°C in a refrigerated environment, protected from light and moisture. An inert gas environment is advisable for long-term storage to prevent oxidation. Handling should be performed by trained personnel using appropriate personal protective equipment (PPE) to ensure safety during weighing and transfer operations.

Global Supply and Logistics

We are committed to being a reliable global manufacturer. Our logistics network ensures timely delivery worldwide, with packaging options tailored to customer needs, typically 25kg cardboard drums or customized solutions. Whether you require sample quantities for R&D or bulk volumes for commercial production, our team is ready to support your project with competitive pricing and dependable service.