4-Bromo-1-Methyl-2-(Trifluoromethyl)Benzene
- CAS No.86845-27-4
- GradeIndustrial / Pharmaceutical
- Availabilityβ In Stock
High-purity 4-Bromo-1-Methyl-2-(Trifluoromethyl)Benzene (CAS 86845-27-4) designed for advanced pharmaceutical and agrochemical synthesis. Available in bulk with certified quality.
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Product Overview
4-Bromo-1-Methyl-2-(Trifluoromethyl)Benzene is a specialized fluorinated aromatic compound widely recognized for its utility in modern organic synthesis. As a critical building block, this intermediate facilitates the construction of complex molecular architectures required in the pharmaceutical and agrochemical industries. The presence of both bromine and trifluoromethyl functional groups provides versatile reactivity, allowing chemists to perform various coupling reactions and substitutions with high efficiency.
Our manufacturing process ensures consistent quality and reliability, making this product a preferred choice for research and industrial scale production. We adhere to strict quality control protocols to guarantee that every batch meets the specified purity standards, supporting your downstream synthesis requirements without compromise.
Key Specifications
The following table outlines the critical physical and chemical properties of this compound. These parameters are essential for process engineers and chemists to determine compatibility with specific reaction conditions and storage requirements.
| Parameter | Value |
|---|---|
| CAS Number | 86845-27-4 |
| Molecular Formula | C8H6BrF3 |
| Molecular Weight | 239.03 g/mol |
| Appearance | Colorless to light yellow liquid |
| Purity | ≥99.0% |
| Boiling Point | 181.8°C at 760 mmHg |
| Density | 1.0 g/cm3 |
| Flash Point | 69.7°C |
| Refractive Index | 1.487 |
Industrial Applications
This fluorinated benzene derivative serves as a vital precursor in the synthesis of active pharmaceutical ingredients (APIs) and advanced agrochemical formulations. The trifluoromethyl group is particularly valued in medicinal chemistry for its ability to enhance metabolic stability and lipophilicity of drug candidates. Consequently, this intermediate is frequently employed in the development of neurological therapeutics and other complex pharmaceutical APIs.
Beyond pharmaceuticals, it finds application in the creation of specialty materials and fine chemicals. The aryl bromide functionality enables palladium-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, which are fundamental steps in building biaryl structures. Our clients utilize this material to streamline their synthesis routes, reducing overall production time and improving yield consistency.
Quality Assurance and Safety
We understand that industrial purity is paramount for successful large-scale manufacturing. Each production lot undergoes rigorous analytical testing, including GC-MS and NMR spectroscopy, to verify identity and purity levels. A Certificate of Analysis (COA) is provided with every shipment, ensuring full traceability and compliance with international chemical safety standards.
Regarding safety, this compound should be handled in accordance with standard laboratory safety practices. It is classified as a flammable liquid due to its flash point. Users are advised to store the material in a tightly closed container within a cool, dry, and well-ventilated area, away from incompatible substances such as strong oxidizing agents. Proper personal protective equipment, including gloves and eye protection, must be worn during handling to prevent skin contact or inhalation of vapors.
Logistics and Supply
As a global manufacturer, we offer flexible packing options to suit diverse operational needs, with standard packaging available in 25kg drums. Our supply chain is optimized for timely delivery, ensuring that your production schedules remain uninterrupted. We are committed to providing competitive bulk pricing without sacrificing quality, supporting our partners in achieving their commercial objectives efficiently.
