Intermediates

4-Bromo-2,3-difluorobenzaldehyde

  • CAS No.644985-24-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Bromo-2,3-difluorobenzaldehyde (CAS 644985-24-0), a key fluorinated intermediate for advanced liquid crystal materials and specialty organic synthesis.

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Product Technical Details

Product Overview

4-Bromo-2,3-difluorobenzaldehyde is a high-value fluorinated aromatic aldehyde widely employed as a critical building block in the synthesis of advanced functional materials. With its precisely positioned bromo and fluoro substituents, this compound offers exceptional reactivity and selectivity in cross-coupling reactions, making it indispensable in the development of next-generation liquid crystal compounds used in high-performance display technologies.

Specifications

Molecular FormulaC₇H₃BrF₂O
Molecular Weight220.999 g/mol
Density1.758 g/cm³
Boiling Point239.859 °C
Flash Point98.864 °C
AppearanceWhite to off-white chunks or crystalline powder
Purity≥99.0%

Industrial Applications

This fluorinated benzaldehyde derivative serves primarily as a synthetic intermediate in the production of liquid crystal monomers and polymers. Its unique electronic and steric profile enables precise molecular engineering for tunable mesophase behavior. Beyond display applications, it is also utilized in the preparation of agrochemicals, pharmaceutical intermediates, and specialty electronic materials requiring thermal and chemical stability.

  • Enables Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions
  • Provides regioselective functionalization due to ortho-fluorine activation
  • Compatible with standard industrial-scale purification and handling protocols

Stored in a cool, well-ventilated area away from oxidizing agents, the product is typically packed in 25 kg fiber drums but can be customized to meet specific client logistics requirements. As a non-controlled, non-hazardous intermediate under major regulatory frameworks, it supports compliant global supply chains for advanced material manufacturers.