4-Bromo-2,6-difluoroanisole
- CAS No.104197-14-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Bromo-2,6-difluoroanisole (CAS 104197-14-0) designed for advanced organic synthesis and pharmaceutical intermediate applications with assay ≥98.0%.
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Product Overview
4-Bromo-2,6-difluoroanisole is a specialized fluorinated aromatic intermediate engineered for precision organic synthesis. As a critical building block, this compound features a unique substitution pattern with bromine and dual fluorine atoms on the anisole ring, enabling diverse downstream functionalization in the development of complex agrochemicals and pharmaceutical active ingredients.
Manufactured under strict quality control protocols, our product ensures exceptional batch-to-batch consistency and high chemical purity. It serves as an essential precursor for constructing fluorinated biaryl systems and heterocyclic structures widely demanded in modern medicinal chemistry.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 104197-14-0 |
| Molecular Formula | C7H5BrF2O |
| Molecular Weight | 223.015 g/mol |
| Appearance | Colorless to light yellow transparent liquid |
| Assay (Purity) | ≥98.0% |
| Density | 1.6±0.1 g/cm³ |
| Boiling Point | 214.2±35.0 °C at 760 mmHg |
| Flash Point | 98.5±10.2 °C |
| Refractive Index | 1.500 |
Industrial Applications
This fluorinated intermediate is primarily utilized in the multi-step synthesis of high-value fine chemicals. Its specific reactivity profile makes it ideal for cross-coupling reactions, nucleophilic aromatic substitutions, and lithiation processes. Key application areas include:
- Synthesis of novel pharmaceutical APIs requiring fluorinated aromatic cores.
- Development of advanced agrochemical formulations with enhanced metabolic stability.
- Production of specialized liquid crystals and electronic chemical materials.
- Research and development of new catalytic systems in organic chemistry.
Quality Assurance and Packaging
We adhere to rigorous international standards for production and testing. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) verifying identity and purity. The product is securely packaged in 200 kg drums or customized containers to maintain integrity during global logistics. Storage recommendations include keeping the material in a cool, well-ventilated area away from incompatible substances to ensure long-term stability.
