Intermediates

4-Bromo-2-Chlorobenzoic Acid

  • CAS No.59748-90-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 4-Bromo-2-Chlorobenzoic Acid (CAS 59748-90-2) for organic synthesis. Available in bulk quantities with comprehensive COA and global shipping options.

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Product Technical Details

Product Overview

4-Bromo-2-Chlorobenzoic Acid is a highly valued halogenated aromatic compound serving as a essential building block in modern organic synthesis. Characterized by the presence of both bromine and chlorine substituents on the benzoic acid backbone, this chemical intermediate offers unique reactivity profiles suitable for cross-coupling reactions and structural modifications. Our facility produces this compound under strict quality control standards to ensure consistency for downstream pharmaceutical and agrochemical applications.

The dual halogen substitution pattern provides versatile sites for selective functionalization, making it a preferred choice for medicinal chemists designing complex molecular architectures. We prioritize industrial purity levels to minimize impurities that could affect reaction yields or downstream processing efficiency.

Technical Specifications

ParameterSpecification
CAS Number59748-90-2
Molecular FormulaC7H4BrClO2
Molecular Weight235.46 g/mol
AppearanceWhite to brown powder
Assay (Purity)≥98.0%
Moisture Content≤0.2%
Melting Point171-175°C
Density1.809 g/cm3
Boiling Point319.1°C

Industrial Applications

This chemical intermediate is predominantly utilized in the synthesis of active pharmaceutical ingredients (APIs) and advanced agrochemical formulations. The bromine and chlorine atoms allow for sequential substitution reactions, enabling the construction of biaryl structures common in drug discovery pipelines. Key application areas include:

  • Pharmaceutical intermediate for kinase inhibitors and anti-inflammatory agents.
  • Precursor in the manufacturing of specialized polymers and liquid crystals.
  • Building block for agrochemical herbicides and fungicides.
  • Reagent in palladium-catalyzed cross-coupling reactions such as Suzuki or Heck couplings.

Quality Assurance and Packaging

Every batch of 4-Bromo-2-Chlorobenzoic Acid undergoes rigorous analytical testing including HPLC, GC, and NMR spectroscopy to verify structural integrity and purity levels. We provide a comprehensive Certificate of Analysis (COA) with each shipment to ensure compliance with international regulatory standards. Our commitment to quality extends to our packaging solutions, designed to maintain product stability during transit.

Standard packaging consists of 25 kg drums lined with moisture-resistant materials. Custom packaging solutions are available upon request to meet specific logistical requirements. We recommend storing the product in a cool, ventilated area away from direct sunlight and incompatible materials to preserve shelf life and chemical stability.