4-Bromo-2-chlorobenzonitrile
- CAS No.154607-01-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Bromo-2-chlorobenzonitrile (CAS 154607-01-9) designed for advanced organic synthesis. Reliable supply with ≥99.0% assay for pharmaceutical intermediates.
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Product Overview
4-Bromo-2-chlorobenzonitrile is a specialized halogenated aromatic nitrile compound that serves as a critical building block in modern organic synthesis. Characterized by its unique substitution pattern featuring both bromine and chlorine atoms on the benzene ring, this chemical intermediate offers versatile reactivity for complex molecular construction. Our facility produces this compound under strict quality control standards to ensure consistency for downstream pharmaceutical and agrochemical applications.
As a key precursor, this nitrile derivative facilitates various cross-coupling reactions and nucleophilic substitutions. The presence of halogen atoms at specific positions allows chemists to selectively functionalize the aromatic ring, making it an invaluable asset in the development of new active pharmaceutical ingredients (APIs) and fine chemicals. We commit to providing a stable supply chain for research and industrial manufacturing needs.
Technical Specifications
Our production process emphasizes high purity and precise physical properties to meet the rigorous demands of synthetic chemistry. The following table outlines the standard specifications for our commercial grade material. Each batch is accompanied by a Certificate of Analysis (COA) to verify compliance with stated parameters.
| Parameter | Specification |
|---|---|
| Chemical Name | 4-Bromo-2-chlorobenzonitrile |
| CAS Number | 154607-01-9 |
| Molecular Formula | C7H3BrClN |
| Molecular Weight | 216.462 g/mol |
| Appearance | White to off-white crystalline powder |
| Assay (Purity) | ≥99.0% |
| Melting Point | 67-68 °C |
| Boiling Point | 279.8±20.0 °C at 760 mmHg |
| Density | 1.7±0.1 g/cm3 |
| Flash Point | 123.0±21.8 °C |
Industrial Applications
This compound is primarily utilized as an intermediate in the synthesis of complex organic molecules. Its structural features make it suitable for palladium-catalyzed coupling reactions such as Suzuki, Heck, and Sonogashira couplings. The nitrile group provides a handle for further transformation into amines, acids, or tetrazoles, expanding its utility in medicinal chemistry pipelines.
- Pharmaceutical Intermediate: Used in the construction of heterocyclic compounds and drug candidates.
- Agrochemical Synthesis: Serves as a precursor for herbicides and fungicides requiring halogenated aromatic cores.
- Material Science: Applied in the development of organic electronic materials and polymers.
- Custom Synthesis: Available for bespoke research projects requiring high-purity building blocks.
Quality Assurance and Storage
We maintain a robust quality management system to ensure every drum meets international standards. Our analytical team employs HPLC and GC methods to verify purity levels before shipment. Proper storage is essential to maintain product integrity. The material should be kept in a cool, ventilated area away from direct sunlight and moisture. Containers must be tightly sealed when not in use to prevent degradation or contamination.
Packaging options include standard 25 kg drums, with flexibility to accommodate specific customer requirements for bulk orders. We prioritize safety during logistics and provide all necessary documentation for hazardous material transport. For technical inquiries or volume pricing, our sales team is ready to assist with prompt quotations and sample availability.
