Intermediates

4-Bromo-2-chlorobenzotrifluoride

  • CAS No.467435-07-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Bromo-2-chlorobenzotrifluoride liquid designed for advanced organic synthesis and pharmaceutical intermediate manufacturing.

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Product Technical Details

Product Overview

4-Bromo-2-chlorobenzotrifluoride is a highly specialized halogenated aromatic compound that serves as a critical building block in modern organic synthesis. Characterized by the presence of bromine, chlorine, and trifluoromethyl substituents on the benzene ring, this chemical offers unique reactivity profiles essential for constructing complex molecular architectures. Our facility produces this intermediate under strict quality control standards to ensure consistency across batches, making it an ideal choice for research and industrial scale applications.

The introduction of fluorine atoms into organic molecules often enhances metabolic stability and lipophilicity, which is why this compound is frequently utilized in the development of advanced pharmaceutical agents and agrochemical formulations. As a versatile precursor, it enables chemists to perform various substitution reactions, including cross-coupling and nucleophilic aromatic substitutions, with high efficiency.

Key Specifications

ParameterValue
CAS Number467435-07-0
Molecular FormulaC7H3BrClF3
Molecular Weight259.451 g/mol
AppearanceColorless transparent liquid
Purity (Assay)≥98.0%
Density1.7±0.1 g/cm3
Boiling Point224.1±35.0 °C at 760 mmHg
Flash Point89.3±25.9 °C

Industrial Applications

This fluorinated intermediate is predominantly employed in the synthesis of high-value fine chemicals. In the pharmaceutical sector, it acts as a key starting material for creating novel drug candidates where specific halogen positioning is required for biological activity. The trifluoromethyl group contributes to improved binding affinity and pharmacokinetic properties in final therapeutic products.

Beyond pharmaceuticals, this compound finds utility in the agrochemical industry for developing robust pesticides and herbicides. Its chemical stability allows it to withstand harsh environmental conditions while maintaining efficacy. Additionally, material science researchers utilize this building block for creating specialized polymers and liquid crystals that require precise electronic properties derived from halogenated aromatic structures.

Quality Assurance and Safety

We adhere to rigorous manufacturing processes to guarantee the industrial purity of every drum shipped. Each batch undergoes comprehensive analysis using gas chromatography and mass spectrometry to verify composition and detect impurities. A Certificate of Analysis (COA) is provided with every order to document compliance with specified parameters.

Regarding safety, this substance should be handled in a well-ventilated environment using appropriate personal protective equipment. It is classified as a chemical intermediate and must be stored in cool, dry conditions away from incompatible materials. Our packaging options include standard 200 kg drums, with custom solutions available to meet specific logistical requirements for global shipping.