4-Bromo-2-fluoro-1-methoxybenzene
- CAS No.2357-52-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Bromo-2-fluoro-1-methoxybenzene (CAS 2357-52-0) supplied for advanced organic synthesis. Reliable bulk availability with strict quality control.
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Product Overview
4-Bromo-2-fluoro-1-methoxybenzene is a highly valued fluorinated aromatic intermediate utilized extensively in modern medicinal chemistry and agrochemical synthesis. As a key building block, this compound facilitates the introduction of both bromine and fluorine substituents onto aromatic rings, enabling diverse downstream transformations. Our facility produces this chemical under stringent quality management systems to ensure consistency and reliability for large-scale industrial applications.
The presence of the methoxy group alongside halogen substituents makes this molecule particularly versatile for nucleophilic aromatic substitution and cross-coupling reactions. Researchers and process chemists rely on this intermediate for developing complex pharmaceutical APIs and advanced functional materials. We commit to supplying material that meets or exceeds standard industry specifications for purity and physical properties.
Technical Specifications
Our production process ensures high chemical integrity. The following table outlines the critical physical and chemical parameters verified during our quality control inspections. Each batch is accompanied by a Certificate of Analysis (COA) to guarantee compliance with stated specifications.
| Parameter | Specification |
|---|---|
| CAS Number | 2357-52-0 |
| Molecular Formula | C7H6BrFO |
| Molecular Weight | 205.02 g/mol |
| Appearance | Colorless liquid |
| Purity | ≥99.0% |
| Density | 1.59 g/mL at 25 °C |
| Boiling Point | 84 °C at 7 mm Hg |
| Melting Point | 16 °C |
| Refractive Index | 1.545 |
Industrial Applications
This fluorinated intermediate serves as a crucial precursor in the synthesis of various bioactive compounds. Its specific substitution pattern allows for selective functionalization, which is essential in multi-step synthetic routes. Common applications include the manufacture of pharmaceutical intermediates, liquid crystal materials, and specialized polymers.
- Used in Suzuki and Buchwald-Hartwig cross-coupling reactions.
- Employed as a starting material for fluorinated drug candidates.
- Utilized in the development of agrochemical active ingredients.
- Serves as a building block for advanced organic electronic materials.
- Compatible with various Grignard and lithiation protocols.
Quality Assurance and Safety
We maintain a robust quality assurance protocol involving gas chromatography and high-performance liquid chromatography to verify purity levels. Safety is paramount in handling halogenated compounds. This product should be stored in a tightly closed container within a cool, dry, and well-ventilated area. It must be kept away from incompatible substances such as strong oxidizing agents.
Our logistics team ensures secure packaging, typically in 25kg drums, suitable for global transportation. We adhere to international shipping regulations for chemical goods. For detailed safety information, users should refer to the provided Material Safety Data Sheet (MSDS). Our technical support team is available to assist with storage guidelines and handling procedures to ensure workplace safety.
Supply Chain Reliability
As a dedicated manufacturer, we offer stable supply chains for bulk quantities. Our production capacity allows us to meet demanding project timelines without compromising on quality. We understand the critical nature of raw material availability in pharmaceutical and chemical manufacturing. Contact our sales team for current inventory status, custom synthesis options, and competitive bulk pricing structures tailored to your specific project requirements.
