Intermediates

4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene

  • CAS No.105529-58-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene designed for advanced organic synthesis and pharmaceutical intermediate applications.

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Product Technical Details

Product Overview

4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene is a specialized fluorinated aromatic compound engineered for precision organic synthesis. As a key building block in modern chemical manufacturing, this substance features a unique structural arrangement combining bromine, fluorine, and trifluoromethoxy functional groups on a benzene ring. This specific substitution pattern enhances its reactivity and versatility, making it an invaluable asset for researchers and industrial chemists developing next-generation pharmaceuticals and agrochemicals.

Our manufacturing process adheres to strict quality control protocols to ensure consistent molecular integrity. The compound is synthesized using advanced fluorination techniques that maximize yield while minimizing impurities. Each batch undergoes rigorous analytical testing, including gas chromatography and nuclear magnetic resonance spectroscopy, to verify compliance with international standards. This commitment to quality ensures that downstream synthesis reactions proceed efficiently without unexpected side reactions caused by contaminants.

Technical Specifications

ParameterValue
Chemical Name4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene
CAS Number105529-58-6
Molecular FormulaC7H3BrF4O
Molecular Weight258.99600 g/mol
Purity≥99.0%
AppearanceColourless to yellow liquid
Density1.724 g/cm3
Boiling Point78oC
Flash Point72.5oC
Refractive Index1.459

Industrial Applications

This fluorinated intermediate serves as a critical precursor in the synthesis of complex organic molecules. Its primary utility lies in the pharmaceutical sector, where it facilitates the construction of bioactive compounds requiring specific halogen substitution patterns. The presence of the trifluoromethoxy group often enhances metabolic stability and lipophilicity in final drug candidates, making this intermediate highly sought after for medicinal chemistry programs.

Beyond pharmaceuticals, this compound finds application in agrochemical development, particularly in the creation of novel herbicides and pesticides. The chemical stability provided by the fluorine atoms allows for durable performance in various environmental conditions. Additionally, materials science researchers utilize this building block for developing specialized polymers and liquid crystals where precise electronic properties are required.

Quality Assurance and Safety

We prioritize safety and reliability in every shipment. Our facility operates under comprehensive safety management systems to handle fluorinated compounds responsibly. The product is classified as a flammable liquid, requiring appropriate storage conditions to maintain stability and prevent hazards. We recommend storing the material in a cool, ventilated area away from direct sunlight and incompatible substances.

Every order is accompanied by a Certificate of Analysis (COA) detailing the specific batch parameters. Our logistics team ensures secure packaging using industry-standard drums or custom containers based on client requirements. With a global supply chain network, we guarantee timely delivery while maintaining the integrity of the chemical product throughout transit. Partner with us for reliable access to high-performance chemical intermediates that drive innovation in your research and production processes.