4-Bromo-2-fluorobenzaldehyde

Product Overview

4-Bromo-2-fluorobenzaldehyde is a highly valued fluorinated aromatic intermediate utilized extensively in the pharmaceutical and agrochemical industries. This compound features a unique substitution pattern on the benzene ring, combining both bromine and fluorine atoms alongside a reactive aldehyde group. Such structural characteristics make it an essential building block for constructing complex molecular architectures. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding synthetic routes.

The presence of the fluorine atom enhances metabolic stability and lipophilicity in downstream drug candidates, while the bromine substituent offers a versatile handle for cross-coupling reactions. This dual functionality allows chemists to perform sequential transformations with high selectivity. We supply this material as a light yellow crystalline solid, packaged to maintain stability during transit and storage.

Key Specifications

Quality control is paramount in our production facility. Each batch undergoes rigorous testing using advanced analytical techniques including HPLC, GC, and NMR spectroscopy to verify identity and purity. The following table outlines the standard specifications for our commercial grade material.

Industrial Applications

This intermediate serves as a critical precursor in the synthesis of various biologically active compounds. The aldehyde group facilitates reactions such as reductive amination, Wittig olefination, and condensation reactions. Meanwhile, the halogen atoms enable palladium-catalyzed cross-couplings like Suzuki-Miyaura or Buchwald-Hartwig reactions. These transformations are fundamental in developing new pharmaceutical APIs and specialized agrochemical agents.

Researchers value this compound for its reliability in multi-step synthesis pathways. It is particularly useful in creating heterocyclic structures where precise positioning of substituents is required. Our global clientele includes research laboratories and large-scale production facilities that depend on our consistent supply chain and technical support.

Storage and Handling

To maintain optimal quality, 4-Bromo-2-fluorobenzaldehyde should be stored in a cool, ventilated area away from direct sunlight and moisture. The material is stable under recommended conditions but should be kept in tightly sealed containers to prevent oxidation or contamination. Standard safety precautions apply during handling, including the use of appropriate personal protective equipment.

We offer flexible packaging options including 25 kg drums or customized solutions based on specific customer requirements. Our logistics team ensures timely global delivery with full documentation including Certificate of Analysis and Material Safety Data Sheet. Contact our sales team for bulk pricing and technical inquiries regarding this specialized chemical intermediate.