Intermediates

4-Bromo-2-fluorobenzenesulfonamide

  • CAS No.214210-30-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Bromo-2-fluorobenzenesulfonamide (CAS 214210-30-7) designed for advanced organic synthesis and pharmaceutical intermediate applications.

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Product Technical Details

Product Overview

4-Bromo-2-fluorobenzenesulfonamide represents a critical fluorinated building block within the realm of modern medicinal chemistry and organic synthesis. As a specialized aryl sulfonamide derivative, this compound features a unique substitution pattern incorporating both bromine and fluorine atoms on the benzene ring. This specific halogenation profile enhances its reactivity and versatility, making it an indispensable precursor for the development of novel pharmaceutical agents, agrochemicals, and functional materials. Our manufacturing process ensures exceptional batch-to-batch consistency, adhering to strict quality control protocols suitable for research and industrial scale applications.

Technical Specifications

We maintain rigorous standards for all chemical intermediates supplied. The following table outlines the key physical and chemical parameters verified through advanced analytical techniques including HPLC, NMR, and mass spectrometry. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) to guarantee compliance with specified purity levels.

ParameterSpecification
CAS Number214210-30-7
Molecular FormulaC6H5BrFNO2S
Molecular Weight254.08 g/mol
AppearanceWhite crystal powder
Assay (Purity)≥99.0%
Moisture Content≤0.2%
Density1.279 g/cm3
Boiling Point240.4 °C
Flash Point95.6 °C

Industrial Applications

This fluorinated sulfonamide serves primarily as a high-value intermediate in the synthesis of complex organic molecules. The presence of the bromine atom facilitates cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, while the fluorine substituent often improves metabolic stability and bioavailability in final drug candidates. Common application areas include:

  • Pharmaceutical drug discovery and structure-activity relationship (SAR) studies.
  • Synthesis of kinase inhibitors and receptor modulators.
  • Development of specialized agrochemical formulations.
  • Production of advanced functional materials and polymers.

Quality Assurance and Safety

Our facility operates under stringent quality management systems to ensure product integrity. Every batch undergoes multi-stage testing to verify identity, purity, and impurity profiles. We understand the importance of supply chain reliability for our B2B partners. Regarding safety, this compound should be handled in accordance with standard laboratory safety practices. It is recommended to use appropriate personal protective equipment (PPE) including gloves and safety goggles during handling. Storage should be maintained in a cool, ventilated environment away from incompatible materials to preserve stability.

Packaging and Logistics

To ensure safe transit and maintain product quality, 4-Bromo-2-fluorobenzenesulfonamide is typically packaged in 25 kg drums. However, we offer flexible packaging solutions tailored to specific customer requirements, including smaller quantities for research purposes or bulk containers for large-scale manufacturing. Our logistics team coordinates global shipping to ensure timely delivery while complying with all international chemical transport regulations. Contact our sales team for detailed shipping information and customized supply agreements.