Intermediates

4-Bromo-2-fluorobenzoic acid

  • CAS No.112704-79-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Bromo-2-fluorobenzoic acid designed for advanced organic synthesis applications. Available in bulk quantities with full quality documentation.

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Product Technical Details

Product Overview

4-Bromo-2-fluorobenzoic acid represents a critical fluorinated building block within the realm of modern organic chemistry. As a specialized intermediate, this compound is extensively utilized in the development of complex pharmaceutical agents and advanced agrochemical formulations. The strategic positioning of both bromine and fluorine substituents on the benzoic acid backbone provides unique reactivity profiles, enabling chemists to execute selective transformations with high precision. Our manufacturing facility is dedicated to producing this material under stringent quality control standards to ensure consistency across every batch.

The incorporation of fluorine atoms into organic molecules is a cornerstone strategy in medicinal chemistry, often enhancing metabolic stability and bioavailability. Consequently, 4-Bromo-2-fluorobenzoic acid serves as an essential precursor for synthesizing biologically active compounds. We understand the critical nature of supply chain reliability for research and production teams, which is why we maintain robust inventory levels and offer flexible logistics solutions to meet global demand.

Technical Specifications

Our production process employs advanced synthesis routes to achieve superior purity levels suitable for sensitive downstream applications. Each batch undergoes rigorous analytical testing using high-performance liquid chromatography and nuclear magnetic resonance spectroscopy to verify chemical identity and purity. The physical properties of this material are consistent with established literature values, ensuring predictable behavior during reaction scaling.

ParameterSpecification
CAS Number112704-79-7
Molecular FormulaC7H4BrFO2
Molecular Weight219.01 g/mol
AppearanceWhite to off-white crystalline powder
Purity≥99.0%
Moisture Content≤0.5%
Melting Point211-215°C
Density1.789 g/cm3

Quality Assurance and Manufacturing

Quality is the foundation of our operation. We implement a comprehensive quality management system that covers every stage from raw material sourcing to final product dispatch. Our technical team conducts regular audits of the manufacturing process to identify and mitigate potential risks. Certificates of Analysis are provided with every shipment, detailing specific batch data including assay results, impurity profiles, and physical constants. This transparency allows our partners to integrate our materials into their workflows with complete confidence.

  • Strict adherence to international safety and quality standards.
  • Advanced analytical equipment for precise verification.
  • Batch traceability for full supply chain visibility.
  • Responsive technical support for application guidance.

Industrial Applications

This fluorinated intermediate is primarily employed in the synthesis of pharmaceuticals where specific substitution patterns are required. It is particularly valuable in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, where the bromo group acts as a reactive handle. Additionally, the carboxylic acid functionality allows for further derivatization into esters, amides, or acid chlorides. Beyond pharmaceuticals, this compound finds utility in the development of novel materials and specialized fine chemicals requiring high structural integrity.

Storage and Handling

To maintain optimal stability, 4-Bromo-2-fluorobenzoic acid should be stored in a cool, ventilated environment away from direct sunlight and moisture. Containers must be kept tightly sealed when not in use to prevent hydration or contamination. Standard laboratory safety protocols should be followed during handling, including the use of appropriate personal protective equipment. We offer packaging options tailored to customer needs, typically supplying in 25 kg drums, with custom packaging available upon request to facilitate efficient transport and storage.