4-Bromo-2-fluorobenzyl bromide
- CAS No.76283-09-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Bromo-2-fluorobenzyl bromide designed for advanced organic synthesis and pharmaceutical intermediate applications.
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Product Overview
4-Bromo-2-fluorobenzyl bromide represents a critical halogenated building block within the realm of modern organic chemistry. Characterized by its unique substitution pattern featuring both bromine and fluorine atoms on the benzyl structure, this compound serves as an essential precursor for the development of complex pharmaceutical agents and agrochemical formulations. Our manufacturing process ensures consistent quality, making it a reliable choice for research laboratories and industrial-scale synthesis operations requiring precise molecular architecture.
The presence of the fluorine atom enhances the metabolic stability and lipophilicity of downstream products, while the bromomethyl group offers a reactive site for various nucleophilic substitution reactions. This dual functionality allows chemists to construct diverse molecular scaffolds efficiently. As a dedicated manufacturer, we prioritize purity and structural integrity to support high-yield transformations in multi-step synthesis pathways.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 4-Bromo-2-fluorobenzyl bromide |
| CAS Registry Number | 76283-09-5 |
| Molecular Formula | C7H5Br2F |
| Molecular Weight | 267.92 g/mol |
| Appearance | Off-white to white solid |
| Purity (GC) | ≥99.0% |
| Density | 1.923 g/cm3 |
| Melting Point | 33-36°C |
| Boiling Point | 126°C |
| Refractive Index | 1.583 |
Industrial Applications
This specialized intermediate is predominantly utilized in the synthesis of active pharmaceutical ingredients (APIs) where fluorinated aromatic structures are required. The compound facilitates cross-coupling reactions and serves as a key electrophile in alkylation processes. Its high reactivity profile makes it suitable for generating libraries of compounds during drug discovery phases. Additionally, it finds application in the production of advanced materials and fine chemicals where specific halogen positioning is crucial for final product performance.
Researchers value this material for its compatibility with various catalytic systems, enabling streamlined workflows in medicinal chemistry. Whether used for developing neurological therapeutics or cardiovascular medications, the reliability of the starting material directly impacts the success rate of the final synthesis. Our supply chain is optimized to deliver this chemical with minimal lead times to support continuous production schedules.
Quality Assurance and Storage
Quality control is paramount in our production facility. Each batch undergoes rigorous testing using gas chromatography and nuclear magnetic resonance spectroscopy to confirm identity and purity levels. We provide a comprehensive Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with international standards. Our packaging solutions are designed to maintain stability during transit, protecting the product from moisture and light exposure.
- Stored in a cool, ventilated area away from incompatible substances.
- Packaged in 25 kg drums or customized containers based on client requirements.
- Strict adherence to safety data sheet (SDS) guidelines during handling.
- Long-term stability ensured through proper sealing and environmental control.
For large-scale procurement or technical inquiries regarding synthesis routes, our expert team is available to provide detailed support. We are committed to fostering long-term partnerships through consistent product quality and responsive customer service.
