4-Bromo-2-methylbenzoic acid
- CAS No.68837-59-2
- GradeIndustrial / Pharmaceutical
- Availabilityβ In Stock
High-purity 4-Bromo-2-methylbenzoic acid (CAS 68837-59-2) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical intermediates.
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Product Overview
4-Bromo-2-methylbenzoic acid is a specialized aromatic carboxylic acid derivative that serves as a critical building block in modern organic synthesis. Characterized by its bromine substituent at the para position and a methyl group at the ortho position relative to the carboxylic acid functionality, this compound offers unique reactivity profiles essential for complex molecule construction. Our manufacturing process ensures consistent quality, making it an ideal choice for research laboratories and industrial-scale production facilities focusing on fine chemicals and pharmaceutical intermediates.
This chemical entity is highly valued for its stability and versatility in cross-coupling reactions. The presence of the bromine atom facilitates various catalytic transformations, while the carboxylic acid group allows for further functionalization into esters, amides, or acid chlorides. We prioritize purity and safety in every batch produced, adhering to international standards for chemical manufacturing.
Technical Specifications
To guarantee performance in sensitive synthetic routes, we maintain rigorous control over physical and chemical parameters. The following table outlines the standard specifications for our commercial grade material. Custom specifications may be available upon request for specific project requirements.
| Parameter | Specification |
|---|---|
| CAS Number | 68837-59-2 |
| Molecular Formula | C8H7BrO2 |
| Molecular Weight | 215.044 g/mol |
| Appearance | Off-white to slight yellow crystalline powder |
| Assay (Purity) | ≥98.0% |
| Melting Point | 180-184 °C |
| Moisture Content | ≤0.5% |
| Density | 1.6±0.1 g/cm3 |
Industrial Applications
The primary utility of 4-Bromo-2-methylbenzoic acid lies in its role as a versatile intermediate for the synthesis of active pharmaceutical ingredients (APIs) and agrochemical compounds. Medicinal chemists frequently utilize this building block in Suzuki-Miyaura coupling reactions to construct biaryl structures found in many kinase inhibitors and anti-inflammatory agents. Additionally, it serves as a precursor for ligand development in catalytic systems.
Beyond pharmaceuticals, this compound is employed in the production of advanced polymers and functional materials where specific substitution patterns on the benzene ring are required. The methyl group provides steric hindrance that can influence the regioselectivity of subsequent reactions, offering chemists greater control over synthetic pathways. Our supply chain supports both small-scale discovery projects and large-scale commercial manufacturing needs.
Quality Assurance and Storage
Quality is the cornerstone of our operation. Each production lot undergoes comprehensive analysis using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment to ensure full traceability and compliance with your internal quality standards.
For optimal preservation of chemical integrity, store this product in a cool, ventilated area away from direct sunlight and moisture. The material should be kept in tightly sealed containers to prevent hydration or contamination. We offer flexible packaging options, including standard 25 kg drums, with customization available to suit specific logistical requirements. Our global distribution network ensures timely delivery while maintaining all necessary safety documentation for hazardous materials transport.
