4-Bromo-2-Nitro-1-(Trifluoromethyl)Benzene
- CAS No.251115-21-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Bromo-2-Nitro-1-(Trifluoromethyl)Benzene liquid for pharmaceutical synthesis. Reliable supply with COA.
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Product Overview
4-Bromo-2-Nitro-1-(Trifluoromethyl)Benzene is a specialized fluorinated aromatic compound designed for advanced organic synthesis and pharmaceutical development. This chemical building block features a unique substitution pattern comprising a bromo group, a nitro group, and a trifluoromethyl moiety on a benzene ring. Such structural complexity makes it an invaluable precursor in the construction of novel therapeutic agents and agrochemical formulations.
Our manufacturing process ensures exceptional consistency and quality. The presence of the trifluoromethyl group significantly enhances the metabolic stability and lipophilicity of downstream drug candidates, which is a critical parameter in modern medicinal chemistry. As a trusted global manufacturer, we provide this intermediate with rigorous quality control standards to support your research and production needs.
Technical Specifications
We adhere to strict quality assurance protocols to guarantee the performance of our chemicals. The following table outlines the key physical and chemical properties verified during our batch testing procedures.
| Parameter | Specification |
|---|---|
| CAS Number | 251115-21-6 |
| Molecular Formula | C7H3BrF3NO2 |
| Molecular Weight | 270.00 g/mol |
| Appearance | Colorless Transparent Liquid |
| Purity | ≥99.0% |
| Density | 1.788 g/cm3 |
| Boiling Point | 268.9ºC at 760 mmHg |
| Flash Point | 116.4ºC |
| Refractive Index | 1.514 |
Industrial Applications
This fluorinated intermediate serves primarily as a key starting material in the synthesis of complex pharmaceutical APIs. The bromo substituent allows for versatile cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, enabling chemists to introduce diverse functional groups efficiently. Meanwhile, the nitro group can be reduced to an amine, opening pathways for further derivatization into heterocycles or amides.
- Pharmaceutical Intermediate: Used in the development of kinase inhibitors and receptor modulators.
- Agrochemical Synthesis: Employed in the creation of advanced herbicides and pesticides.
- Material Science: Utilized in the preparation of specialized polymers and liquid crystals.
- Custom Synthesis: Available for bespoke research projects requiring high-purity fluorinated blocks.
Storage and Handling
To maintain the integrity of 4-Bromo-2-Nitro-1-(Trifluoromethyl)Benzene, proper storage conditions are essential. The product should be kept in a tightly closed container to prevent moisture absorption and contamination. It is recommended to store the material in a cool, dry, and well-ventilated area away from direct sunlight and incompatible substances. Always refer to the Safety Data Sheet (SDS) for comprehensive handling instructions and personal protective equipment requirements.
We offer flexible packing options based on customer requests, ensuring safe transit for both laboratory-scale and industrial-scale orders. Our logistics network supports global shipping, providing timely delivery accompanied by a Certificate of Analysis (COA) for every batch.
