Intermediates

4-Bromo-2-Trifluoromethoxyaniline

  • CAS No.175278-09-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Bromo-2-Trifluoromethoxyaniline (CAS 175278-09-8) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical and agrochemical intermediates.

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Product Technical Details

Product Overview

4-Bromo-2-Trifluoromethoxyaniline is a specialized fluorinated organic compound widely recognized for its utility in complex chemical synthesis pathways. As a key building block, this substance features a unique structural combination of bromo and trifluoromethoxy functional groups attached to an aniline backbone. This specific arrangement enhances its reactivity and stability, making it an invaluable asset for research and industrial production teams focused on developing advanced molecular structures. Our facility ensures that every batch meets rigorous international standards for purity and consistency.

The compound is primarily utilized as a critical intermediate in the manufacture of various high-value chemicals. Due to the presence of the trifluoromethoxy group, it offers improved metabolic stability and lipophilicity when incorporated into larger molecular frameworks. This characteristic is particularly sought after in the design of novel agrochemical agents and pharmaceutical candidates where specific electronic and steric properties are required to achieve desired biological activity.

Chemical Specifications

We maintain strict quality assurance protocols to guarantee the performance of this chemical in your synthesis processes. The physical properties are carefully monitored to ensure compatibility with standard reaction conditions. Below are the key technical parameters associated with this product grade:

ParameterSpecification
CAS Number175278-09-8
Molecular FormulaC7H5BrF3NO
Molecular Weight256.02 g/mol
AppearanceOff-white to white powder
Purity (GC)≥99.0%
Density1.691 g/cm3
Boiling Point98-100oC
Flash Point230oF
Refractive Index1.513

Industrial Applications

This fluorinated aniline derivative serves as a versatile precursor in multiple sectors of the fine chemical industry. Its primary application lies in organic synthesis where it acts as a nucleophile or coupling partner in cross-coupling reactions. The bromo substituent allows for palladium-catalyzed transformations, while the trifluoromethoxy group provides distinct electronic effects that can tune the properties of the final product.

  • Pharmaceutical Intermediate Synthesis: Used in the development of new therapeutic agents requiring fluorinated aromatic structures.
  • Agrochemical Formulation: Employed in the creation of herbicides and pesticides with enhanced environmental stability.
  • Material Science: Utilized in the production of specialized polymers and liquid crystal materials.
  • Research and Development: Essential for academic and industrial labs exploring new chemical spaces.

Quality Assurance and Handling

Safety and quality are paramount in our operations. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) that verifies the identity and purity of the material. We recommend storing this product in a cool, ventilated area away from direct sunlight and moisture to maintain its integrity over time. Proper personal protective equipment should be worn during handling to ensure safety in the workplace.

Our packaging options are designed to meet the needs of both laboratory-scale research and large-scale industrial production. Standard packaging includes 25 kg drums, but we offer flexible solutions based on specific customer requirements. As a global manufacturer, we are committed to providing reliable supply chains, competitive bulk pricing, and expert technical support to assist with your synthesis routes and manufacturing processes.