4-Bromo-2-(Trifluoromethyl) Benzoic Acid
- CAS No.320-31-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity organic synthesis intermediate featuring a trifluoromethyl group for advanced pharmaceutical and agrochemical development.
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Product Overview
4-Bromo-2-(Trifluoromethyl) Benzoic Acid is a highly specialized fluorinated aromatic compound designed for use as a critical building block in complex organic synthesis. This chemical entity combines the reactivity of a bromo substituent with the electronic and lipophilic properties of a trifluoromethyl group, making it an invaluable asset for medicinal chemists and industrial researchers. Our manufacturing process ensures consistent quality and high purity levels, catering to the rigorous demands of modern pharmaceutical and agrochemical development pipelines.
The presence of the trifluoromethyl moiety significantly enhances the metabolic stability and bioavailability of downstream molecules, while the bromine atom offers a versatile handle for palladium-catalyzed cross-coupling reactions. This dual functionality allows for the efficient construction of diverse molecular architectures required in next-generation therapeutic agents.
Key Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 4-Bromo-2-(Trifluoromethyl) Benzoic Acid |
| CAS Number | 320-31-0 |
| Molecular Formula | C8H4BrF3O2 |
| Molecular Weight | 269.015 g/mol |
| Purity (Assay) | ≥98.0% |
| Appearance | Off-white powder |
| Density | 1.8±0.1 g/cm3 |
| Boiling Point | 275.2±40.0 °C at 760 mmHg |
| Flash Point | 120.2±27.3 °C |
Industrial Applications
This compound serves primarily as a versatile intermediate in the synthesis of advanced organic materials. Its primary utility lies in the pharmaceutical sector, where it is employed in the development of novel drug candidates requiring fluorinated aromatic structures. The chemical is particularly suited for Suzuki-Miyaura and Buchwald-Hartwig coupling reactions, enabling the formation of carbon-carbon and carbon-nitrogen bonds with high precision.
Beyond pharmaceuticals, this benzoic acid derivative finds application in agrochemical research, contributing to the creation of robust herbicides and pesticides. The stability imparted by the fluorine atoms ensures longevity and efficacy in various environmental conditions. Researchers also utilize this material in the synthesis of liquid crystals and specialized polymers where specific electronic properties are required.
Quality Assurance and Handling
We adhere to strict quality control protocols to ensure every batch meets international standards. Each production lot undergoes comprehensive analysis using HPLC and NMR spectroscopy to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment to guarantee transparency and compliance with your internal quality systems.
- Consistent batch-to-batch reproducibility
- Low impurity profile suitable for sensitive reactions
- Comprehensive documentation support including MSDS
- Flexible packaging options to suit laboratory or industrial scale
For optimal stability, the product should be stored in a cool, ventilated area away from direct sunlight and moisture. Containers must be kept tightly sealed when not in use to prevent degradation. Our logistics team ensures safe and compliant global shipping, utilizing appropriate packaging materials such as 25 kg drums or customized solutions based on client requirements. We are committed to supporting your research and production goals with reliable supply chain solutions and technical expertise.
