Intermediates

4-Bromo-3,5-difluoroaniline

  • CAS No.203302-95-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Bromo-3,5-difluoroaniline intermediate for advanced organic synthesis. Available in bulk with strict quality control and global shipping.

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Product Technical Details

Product Overview

4-Bromo-3,5-difluoroaniline represents a highly specialized class of fluorinated aromatic amines essential for modern chemical synthesis. This compound features a unique substitution pattern with both bromine and fluorine atoms on the benzene ring, providing versatile reactivity for downstream chemical transformations. As a key building block, it is extensively utilized in the development of pharmaceutical agents, agrochemical formulations, and advanced functional materials. Our facility produces this intermediate under strict quality management systems to ensure consistent molecular integrity and high purity levels suitable for sensitive reaction pathways.

The presence of the bromo group allows for various cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, while the fluorine substituents enhance metabolic stability and lipophilicity in final drug candidates. This dual functionality makes the compound a valuable asset for medicinal chemists aiming to optimize lead compounds. We understand the critical nature of supply chain reliability for research and production scales, which is why we maintain robust inventory levels and flexible packaging options to meet diverse client requirements.

Key Specifications

ParameterValue
CAS Number203302-95-8
Molecular FormulaC6H4BrF2N
Molecular Weight208.003
AppearanceWhite to light pink crystalline powder
Assay≥98.0%
Melting Point99-101°C
Boiling Point223.7±35.0 °C at 760 mmHg
Density1.8±0.1 g/cm3
Flash Point89.1±25.9 °C

Industrial Applications

This fluorinated aniline derivative serves as a pivotal intermediate in the synthesis of complex organic molecules. In the pharmaceutical sector, it is frequently employed in the construction of kinase inhibitors and receptor modulators where fluorine substitution is crucial for bioavailability. The agrochemical industry utilizes this building block for developing novel herbicides and pesticides that require enhanced environmental stability. Additionally, material science researchers leverage its properties for creating polymers with specific thermal and chemical resistance profiles. The versatility of this compound supports innovation across multiple high-tech sectors.

Quality Assurance and Storage

Every batch of 4-Bromo-3,5-difluoroaniline undergoes rigorous analytical testing including HPLC, NMR, and GC-MS to verify identity and purity. We provide a comprehensive Certificate of Analysis (COA) with each shipment to guarantee compliance with specified standards. Proper storage is essential to maintain product stability over time. The material should be kept in a cool, ventilated area away from direct sunlight and moisture sources. Containers must remain tightly sealed when not in use to prevent degradation or contamination. Our packaging solutions include 25 kg drums as standard, with custom options available upon request to suit specific logistical needs. We are committed to delivering safe, compliant, and high-performance chemical solutions to our global partners.