Intermediates

4-Bromo-3-chloro-2-fluoroaniline

  • CAS No.115843-99-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Bromo-3-chloro-2-fluoroaniline (CAS 115843-99-7) designed for advanced organic synthesis. Reliable supply with ≥99.0% assay for pharmaceutical and agrochemical applications.

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Product Technical Details

Product Overview

4-Bromo-3-chloro-2-fluoroaniline is a highly specialized halogenated aromatic amine utilized extensively in the fine chemical and pharmaceutical industries. As a critical building block, this compound features a unique substitution pattern on the aniline ring, providing distinct reactivity profiles for complex molecular construction. Our manufacturing process ensures exceptional purity levels, making it an ideal candidate for demanding synthetic routes where consistency and quality are paramount.

The presence of bromine, chlorine, and fluorine substituents allows for versatile chemical transformations, including nucleophilic aromatic substitution and transition metal-catalyzed cross-coupling reactions. This multifunctional intermediate serves as a foundational component in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemical formulations. We maintain strict quality control protocols to guarantee that every batch meets international standards for industrial usage.

Technical Specifications

Our production facility adheres to rigorous analytical testing procedures to verify the physical and chemical properties of 4-Bromo-3-chloro-2-fluoroaniline. The following table outlines the key specifications associated with this product under standard conditions.

SpecificationValue
CAS Number115843-99-7
Molecular FormulaC6H4BrClFN
Molecular Weight224.458 g/mol
AppearanceLight brown to brown solid
Assay (Purity)≥99.0%
Melting Point51-53 °C
Boiling Point262.7 ± 35.0 °C at 760 mmHg
Density1.8 ± 0.1 g/cm3
Flash Point112.7 ± 25.9 °C

These parameters are verified using high-performance liquid chromatography (HPLC) and gas chromatography (GC) methods. Customers receive a comprehensive Certificate of Analysis (COA) with every shipment to confirm compliance with the stated specifications.

Industrial Applications

This halogenated aniline derivative is primarily employed as a key intermediate in organic synthesis. Its specific halogen arrangement enables selective functionalization, which is crucial for constructing complex heterocyclic systems found in modern medicine. Researchers and process chemists utilize this material for developing kinase inhibitors, receptor modulators, and other therapeutic agents.

Beyond pharmaceuticals, the compound finds application in the agrochemical sector for creating potent herbicides and pesticides. The stability of the carbon-halogen bonds allows for robust performance in various reaction conditions. Additionally, it serves as a valuable precursor in the synthesis of specialty polymers and functional materials where specific electronic properties are required.

Quality Assurance and Safety

We are committed to delivering products that meet the highest safety and quality standards. Our manufacturing process is optimized to minimize impurities and by-products. Each production lot undergoes thorough screening to ensure it is free from hazardous contaminants. Proper handling procedures should be followed according to standard laboratory safety guidelines.

  • Store in a cool, ventilated place away from direct sunlight.
  • Keep containers tightly closed when not in use to prevent moisture absorption.
  • Use appropriate personal protective equipment (PPE) during handling.
  • Ensure adequate ventilation to avoid inhalation of dust or vapors.

Packaging is available in 25 kg drums, with custom options available upon request to suit specific logistical requirements. We support global shipping with secure packaging to maintain product integrity during transit. For bulk orders and technical inquiries, our sales team is ready to provide detailed information and competitive pricing structures.