4-Bromo-3-chloropyridine
- CAS No.73583-41-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 4-Bromo-3-chloropyridine (CAS 73583-41-2) designed for advanced organic synthesis. Reliable bulk supply with full quality documentation for pharmaceutical and agrochemical applications.
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Product Overview
4-Bromo-3-chloropyridine is a highly valued halogenated heterocyclic compound widely utilized in the field of fine chemical synthesis. As a key building block, this pyridine derivative features distinct reactive sites due to the presence of both bromine and chlorine substituents on the aromatic ring. This unique structural configuration allows chemists to perform selective cross-coupling reactions, making it an indispensable intermediate for constructing complex molecular architectures.
Our manufacturing process ensures consistent quality and high purity levels, meeting the rigorous demands of modern medicinal chemistry and agricultural science. We specialize in supplying this material to research institutions and industrial partners who require reliable raw materials for scalable production processes.
Key Chemical Properties
The chemical stability and reactivity of 4-Bromo-3-chloropyridine make it suitable for various transformation reactions. The bromine atom at the 4-position is generally more reactive towards palladium-catalyzed coupling than the chlorine at the 3-position, enabling sequential functionalization strategies. This selectivity is crucial for synthesizing diverse libraries of compounds without requiring extensive protecting group chemistry.
With a molecular formula of C5H3BrClN and a molecular weight of 192.441, this compound exhibits favorable physical properties for handling in standard laboratory and plant environments. The boiling point and density specifications ensure compatibility with common solvent systems used in organic synthesis.
Industrial Applications
This intermediate serves as a foundational component in the development of novel pharmaceutical agents. It is frequently employed in the synthesis of kinase inhibitors, receptor modulators, and other therapeutic candidates where the pyridine core is essential for biological activity. Additionally, the agrochemical sector utilizes this building block for creating new generations of pesticides and herbicides with improved environmental profiles.
- Pharmaceutical intermediate for API synthesis
- Ligand development for catalytic processes
- Agrochemical active ingredient precursor
- Material science and functional polymer research
Quality Specifications
We maintain strict quality control protocols to guarantee the integrity of every batch. Our analytical teams verify identity and purity using advanced chromatographic and spectroscopic methods. Customers receive comprehensive documentation, including Certificates of Analysis (COA) and Material Safety Data Sheets (MSDS), to support regulatory compliance and internal quality audits.
| Parameter | Specification |
|---|---|
| CAS Number | 73583-41-2 |
| Molecular Formula | C5H3BrClN |
| Molecular Weight | 192.441 |
| Appearance | Light yellow to brown liquid |
| Assay (Purity) | ≥98.0% |
| Density | 1.7±0.1 g/cm3 |
| Boiling Point | 219.8±20.0 °C at 760 mmHg |
| Flash Point | 86.7±21.8 °C |
Storage and Packaging
To maintain optimal stability, 4-Bromo-3-chloropyridine should be stored in a cool, ventilated area away from direct sunlight and moisture. The product is typically packaged in 200 kg drums, though we offer flexible packaging solutions tailored to specific customer requirements. Proper handling procedures should be followed to ensure safety during transport and usage within chemical facilities.
