Intermediates

4-Bromo-3-fluoroanisole

  • CAS No.408-50-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Bromo-3-fluoroanisole (CAS 408-50-4), a versatile fluoroaromatic intermediate for advanced organic synthesis in pharmaceutical and agrochemical manufacturing.

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Product Technical Details

Product Overview

4-Bromo-3-fluoroanisole is a high-value fluoroaromatic building block widely employed in the synthesis of complex organic molecules. With its unique combination of bromo and fluoro substituents on the anisole scaffold, this compound serves as a strategic intermediate in cross-coupling reactions, enabling the construction of structurally diverse aromatic systems essential to modern medicinal chemistry and crop protection science.

Specifications

Molecular FormulaC7H6BrFO
Molecular Weight205.02 g/mol
AppearanceColorless transparent liquid
Assay≥98.0%
StorageStore in a cool, ventilated place
Packaging10 kg/drum; custom packaging available upon request

Industrial Applications

As a specialized halogenated aromatic ether, 4-Bromo-3-fluoroanisole is primarily utilized as a key intermediate in multi-step synthetic routes. Its reactivity profile makes it particularly suitable for:

  • Suzuki, Stille, and other palladium-catalyzed cross-coupling transformations
  • Construction of fluorinated biaryl motifs found in active pharmaceutical ingredients (APIs)
  • Synthesis of novel agrochemical compounds requiring precise electronic and steric tuning
  • Development of advanced materials with tailored optoelectronic properties

Manufactured under stringent quality control protocols, our 4-Bromo-3-fluoroanisole meets the demanding purity standards required by global R&D and production facilities engaged in cutting-edge chemical innovation.