4-Bromo-3-fluorobenzotrifluoride
- CAS No.40161-54-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Bromo-3-fluorobenzotrifluoride (CAS 40161-54-4) designed for advanced organic synthesis. Reliable supply with ≥99.0% purity for pharmaceutical and agrochemical applications.
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Product Overview
4-Bromo-3-fluorobenzotrifluoride is a highly specialized fluorinated aromatic intermediate essential for modern organic synthesis and medicinal chemistry. Identified by CAS number 40161-54-4, this compound serves as a critical building block in the development of complex pharmaceutical agents and agrochemical formulations. Our facility produces this reagent under strict quality control standards to ensure consistent molecular integrity and performance in downstream reactions.
The unique structural configuration, featuring both bromine and fluorine substituents alongside a trifluoromethyl group, provides exceptional reactivity for cross-coupling reactions and nucleophilic substitutions. This makes it an invaluable asset for chemists aiming to introduce specific fluorinated motifs into larger molecular scaffolds, enhancing metabolic stability and bioavailability in final drug candidates.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 4-Bromo-3-fluorobenzotrifluoride |
| CAS Number | 40161-54-4 |
| Molecular Formula | C7H3BrF4 |
| Molecular Weight | 242.996 g/mol |
| Appearance | Colorless Liquid |
| Purity | ≥99.0% |
| Boiling Point | 154-155°C |
| Density | 1.695 g/cm3 |
| Refractive Index | 1.46 |
Industrial Applications
This fluorinated intermediate is predominantly utilized in the synthesis of high-value pharmaceuticals, including kinase inhibitors and receptor modulators where fluorine substitution is known to improve pharmacokinetic profiles. Additionally, it finds significant application in the agrochemical sector for creating robust pesticides and herbicides that require enhanced environmental stability.
- Pharmaceutical Intermediate: Key precursor for oncology and CNS drug development.
- Agrochemical Synthesis: Used in manufacturing advanced crop protection agents.
- Material Science: Employed in the creation of specialized polymers and liquid crystals.
- Research and Development: Standard reagent for academic and industrial organic chemistry labs.
Quality Assurance and Safety
We understand that purity is paramount in chemical synthesis. Every batch of 4-Bromo-3-fluorobenzotrifluoride undergoes rigorous analytical testing using GC-MS and NMR spectroscopy to verify composition and impurity levels. We provide a comprehensive Certificate of Analysis (COA) with every shipment, ensuring full transparency and compliance with international regulatory standards.
Regarding safety, this compound should be handled in a well-ventilated environment using appropriate personal protective equipment. It is classified as a chemical intermediate and should not be used for direct human consumption without further processing and regulatory approval.
Storage and Logistics
To maintain optimal quality, the product must be stored in a tightly closed container within a cool, dry, and well-ventilated area. Protection from moisture and direct sunlight is recommended to prevent degradation. We offer flexible packaging solutions tailored to customer requirements, ranging from laboratory-scale bottles to industrial drums, ensuring safe global delivery.
As a trusted global manufacturer, we commit to stable supply chains, competitive bulk pricing, and responsive technical support. Partner with us for reliable sourcing of premium fluorinated intermediates that drive your innovation forward.
