4-Bromo-3-fluorophenol
- CAS No.121219-03-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Bromo-3-fluorophenol (CAS 121219-03-2) designed for advanced organic synthesis applications. Available in bulk quantities with comprehensive quality documentation.
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Product Overview
4-Bromo-3-fluorophenol represents a critical class of fluorinated aromatic intermediates utilized extensively within the pharmaceutical and agrochemical industries. As a specialized building block, this compound facilitates the introduction of both bromine and fluorine substituents onto aromatic rings, enabling complex molecular architectures essential for modern drug discovery and development. Our manufacturing facility adheres to strict quality management systems to ensure consistent batch-to-batch reliability.
The presence of the fluorine atom significantly enhances the metabolic stability and lipophilicity of downstream molecules, making this intermediate highly valuable for medicinal chemistry programs. We supply this material with a focus on high purity standards, ensuring minimal impurities that could interfere with sensitive catalytic processes or coupling reactions.
Key Specifications
Quality control is paramount in our production process. Each batch undergoes rigorous analytical testing including HPLC, NMR, and GC-MS to verify identity and purity levels. The physical characteristics are maintained within tight tolerances to support reproducible synthesis outcomes.
| Parameter | Specification |
|---|---|
| CAS Number | 121219-03-2 |
| Molecular Formula | C6H4BrFO |
| Molecular Weight | 190.998 g/mol |
| Appearance | Off-white powder |
| Assay (Purity) | ≥99.0% |
| Melting Point | 71.5°C |
| Boiling Point | 231.4±20.0 °C at 760 mmHg |
| Density | 1.8±0.1 g/cm3 |
Industrial Applications
This fluorinated phenol derivative serves as a versatile precursor in organic synthesis. It is commonly employed in cross-coupling reactions such as Suzuki-Miyaura or Buchwald-Hartwig aminations, where the bromine moiety acts as a leaving group. The fluorine substituent remains intact, providing electronic modulation to the final active pharmaceutical ingredient (API).
- Pharmaceutical Intermediate: Used in the synthesis of kinase inhibitors and receptor modulators.
- Agrochemical Production: Utilized in the development of advanced herbicides and fungicides.
- Material Science: Applied in the creation of specialized polymers and liquid crystals.
Quality Assurance and Packaging
We understand the importance of secure logistics and documentation in the chemical supply chain. All products are accompanied by a Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS). Our packaging options are designed to maintain product integrity during transit.
Standard packaging includes 25 kg drums, though we offer flexible customization to meet specific client requirements. Storage recommendations include keeping the material in a cool, ventilated area away from direct sunlight and moisture to prevent degradation. Our global distribution network ensures timely delivery to research laboratories and manufacturing plants worldwide.
