Intermediates

4-Bromo-3-methylbenzoic acid

  • CAS No.7697-28-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Bromo-3-methylbenzoic acid (CAS 7697-28-1) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for industrial applications.

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Product Technical Details

Product Overview

4-Bromo-3-methylbenzoic acid is a specialized organic compound widely recognized for its utility in complex chemical synthesis pathways. As a halogenated benzoic acid derivative, this substance serves as a critical building block in the development of pharmaceuticals, agrochemicals, and advanced functional materials. Our manufacturing process ensures consistent quality and high purity levels, making it an ideal choice for research and industrial scale production.

This chemical intermediate features a bromine substituent at the para position and a methyl group at the meta position relative to the carboxylic acid group. This specific substitution pattern provides unique reactivity profiles, allowing chemists to perform selective transformations such as cross-coupling reactions, esterifications, and amidations. The stability of the aromatic ring combined with the reactive functional groups makes it a versatile reagent in modern organic chemistry.

Key Specifications

We adhere to strict quality control protocols to guarantee that every batch meets international standards. The following table outlines the typical physical and chemical properties associated with this product.

ParameterValue
CAS Number7697-28-1
Molecular FormulaC8H7BrO2
Molecular Weight215.044 g/mol
AppearancePinkish peach crystalline powder
Assay (Purity)≥98.0%
Melting Point212-216 °C
Boiling Point311.4±30.0 °C at 760 mmHg
Density1.6±0.1 g/cm3
Flash Point142.1±24.6 °C

Industrial Applications

The primary application of 4-Bromo-3-methylbenzoic acid lies in its role as a precursor for more complex molecular structures. In the pharmaceutical sector, it is utilized in the synthesis of various active pharmaceutical ingredients (APIs) where the bromo-methyl-benzoic scaffold is required. Additionally, it finds use in the agrochemical industry for the development of herbicides and pesticides that require specific aromatic substitution patterns.

Researchers value this compound for its compatibility with palladium-catalyzed coupling reactions, such as Suzuki-Miyaura and Heck reactions. These processes are fundamental in constructing biaryl systems and extending carbon chains. The high purity ensures minimal side reactions, leading to improved yields and easier downstream purification processes.

Quality Assurance and Handling

Our facility operates under rigorous quality management systems. Each production batch is accompanied by a Certificate of Analysis (COA) that verifies identity, purity, and physical constants. We recommend storing this material in a cool, ventilated area away from direct sunlight and moisture to maintain stability. Proper personal protective equipment (PPE) should be worn during handling to ensure safety.

We offer flexible packaging options, including standard 25 kg drums, with customization available to meet specific logistical requirements. Our global supply chain ensures timely delivery to laboratories and manufacturing plants worldwide. For bulk inquiries or technical support regarding synthesis routes, our team of experts is ready to assist.