4-Bromoisobenzofuran-1,3-dione

Product Overview

4-Bromoisobenzofuran-1,3-dione, also known as 3-bromophthalic anhydride, is a high-value brominated aromatic compound widely employed as a key building block in complex organic synthesis. With a molecular formula of C8H3BrO3 and a molecular weight of 227.01 g/mol, this specialty intermediate features a reactive anhydride functionality adjacent to a bromine substituent, enabling diverse electrophilic and cross-coupling transformations.

Specifications

Industrial Applications

This brominated phthalic anhydride derivative serves primarily as a critical intermediate in the synthesis of high-performance materials, agrochemicals, and active pharmaceutical ingredients (APIs). Its dual functionality allows for sequential modification—first via nucleophilic ring-opening of the anhydride, followed by palladium-catalyzed coupling reactions (e.g., Suzuki, Heck) at the aryl bromide site. Common downstream applications include the production of liquid crystals, fluorescent dyes, polymer modifiers, and complex heterocyclic scaffolds used in medicinal chemistry.

• Enables regioselective functionalization in multi-step syntheses
• High thermal stability supports robust reaction conditions
• Consistent batch-to-batch quality ensures reliable scale-up
• Compatible with standard industrial handling and purification protocols

Stored in a cool, well-ventilated area away from moisture and oxidizing agents, 4-bromoisobenzofuran-1,3-dione is typically supplied in 25 kg fiber drums or customized packaging to meet global regulatory and logistical requirements.