Intermediates

4-Bromomethyl-2-cyanobiphenyl

  • CAS No.114772-54-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Bromomethyl-2-cyanobiphenyl (CAS 114772-54-2) designed for pharmaceutical API synthesis. Reliable supply for Losartan and Olmesartan production with strict quality control.

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Product Technical Details

Product Overview

4-Bromomethyl-2-cyanobiphenyl is a critical organic intermediate widely utilized in the pharmaceutical industry for the synthesis of advanced therapeutic agents. This compound serves as a fundamental building block in the manufacturing process of angiotensin II receptor blockers, specifically targeting cardiovascular health applications. Our facility produces this chemical with a focus on exceptional purity and consistency, ensuring it meets the rigorous demands of modern drug development pipelines.

As a specialized chemical manufacturer, we understand the importance of supply chain reliability. This product is synthesized using optimized reaction pathways that maximize yield while minimizing impurities. The resulting material exhibits superior stability and reactivity, making it an ideal choice for downstream synthesis operations requiring precise stoichiometric control.

Technical Specifications

ParameterSpecification
CAS Number114772-54-2
Molecular FormulaC14H10BrN
Molecular Weight272.14 g/mol
AppearanceOff-white crystalline powder
Assay≥99.0%
Melting Point125-128°C
Loss on Drying≤0.5%
Related Impurities≤0.5%

Industrial Applications

The primary application of 4-Bromomethyl-2-cyanobiphenyl lies in the production of antihypertensive medications. It acts as a key precursor in the synthesis of Losartan and Olmesartan, which are essential components in managing high blood pressure and related cardiovascular conditions. The high purity level of our intermediate ensures that the final active pharmaceutical ingredients meet international pharmacopoeia standards.

Beyond specific drug synthesis, this compound is valuable for research and development in organic chemistry. Its structural properties allow for versatile functionalization, supporting the creation of novel biphenyl derivatives. Laboratories and production facilities alike benefit from the consistent quality provided by our manufacturing process, which reduces variability in final product outcomes.

Quality Assurance and Packaging

Quality control is paramount in our production facility. Every batch of 4-Bromomethyl-2-cyanobiphenyl undergoes comprehensive testing using high-performance liquid chromatography and other analytical methods. We provide a complete Certificate of Analysis with every shipment, detailing all critical quality attributes including assay, melting point, and impurity profiles.

  • Strict adherence to Good Manufacturing Practices
  • Batch traceability for full supply chain transparency
  • Custom packaging solutions available upon request
  • Global shipping capabilities with secure logistics

Standard packaging consists of 25 kg drums, designed to protect the material from moisture and light during transit. For larger volume requirements, we offer flexible packaging options tailored to customer specifications. Proper storage in a cool, ventilated area ensures the long-term stability of the product, maintaining its chemical integrity until it is ready for use in synthesis reactions.