Intermediates

4-Bromotoluene

  • CAS No.106-38-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 4-Bromotoluene (CAS 106-38-7) is an essential organic intermediate available in bulk quantities. Ideal for pharmaceutical synthesis and chemical research applications.

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Product Technical Details

Product Overview

4-Bromotoluene, frequently referred to as p-Bromotoluene, stands as a vital aromatic halide compound extensively utilized within the realms of organic synthesis and pharmaceutical manufacturing. As a key building block, this chemical intermediate facilitates the construction of complex molecular structures required for advanced material science and medicinal chemistry exploration. Our facility produces this compound under strict quality control measures to ensure consistency and reliability for industrial partners seeking dependable raw materials.

With a CAS registry number of 106-38-7, this substance serves as a fundamental reagent in various coupling reactions, including Suzuki and Heck couplings. The high purity grade available from our production lines makes it suitable for sensitive synthetic pathways where impurity profiles must be tightly managed. We cater to both research laboratories and large-scale production units needing dependable supply chains for continuous operation.

Physical and Chemical Properties

Understanding the physicochemical characteristics of 4-Bromotoluene is essential for safe handling and effective application in synthesis protocols. The compound presents as a colorless to light yellow liquid at standard ambient temperatures, with a distinct aromatic odor typical of substituted benzenes. Its density and boiling point allow for straightforward purification via distillation processes during downstream processing.

The thermal stability and refractive index are critical parameters for quality verification in industrial settings. Our batch testing ensures that every drum meets the specified physical constants, providing confidence to chemists integrating this material into their workflows. Proper characterization supports regulatory compliance and safety data sheet accuracy for global shipping requirements.

Technical Specifications

Parameter Value
Chemical Name 4-Bromotoluene
CAS Number 106-38-7
Molecular Formula C7H7Br
Molecular Weight 171.03 g/mol
Purity ≥99.0%
Appearance Colorless or light yellow liquid
Density 1.39 g/mL at 25 °C
Boiling Point 184 °C
Melting Point 26-29 °C
Refractive Index 1.549

Industrial Applications

This brominated aromatic compound is primarily employed as a precursor in the synthesis of pharmaceuticals, agrochemicals, and functional materials. It acts as an electrophilic partner in cross-coupling reactions, enabling the formation of carbon-carbon bonds essential for creating biologically active molecules. In medicinal chemistry, it is often utilized during the early stages of lead compound optimization and structure-activity relationship studies.

Beyond pharmaceuticals, 4-Bromotoluene finds utility in the production of dyes, pigments, and polymer additives. Its reactivity profile allows for versatile functionalization, making it a preferred choice for process chemists designing scalable synthetic routes. We support clients in scaling up from gram-scale research to tonnage production with consistent quality batches.

Storage and Handling

To maintain product integrity, 4-Bromotoluene should be stored in a cool, well-ventilated warehouse away from direct sunlight and heat sources. It is crucial to keep containers tightly closed when not in use to prevent moisture absorption or contamination. Storage areas must be separated from strong oxidizing agents and foodstuff to comply with international safety regulations.

Personal protective equipment, including gloves and eye protection, is recommended during handling operations. In case of spillage, absorb with inert material and dispose of according to local environmental laws. We provide comprehensive safety data sheets (SDS) with every shipment to ensure workplace safety and regulatory adherence. Packaging is available in 25kg drums or customized according to specific customer logistics requirements.