Intermediates

4-Bromoveratrole

  • CAS No.2859-78-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

4-Bromoveratrole is a high-purity organic synthesis intermediate used in pharmaceutical and agrochemical manufacturing. Available in bulk with strict quality control.

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Product Technical Details

Product Overview

4-Bromoveratrole, chemically known as 4-Bromo-1,2-dimethoxybenzene, serves as a critical building block in the realm of advanced organic synthesis. This aromatic compound features a veratrole core substituted with a bromine atom, making it highly versatile for various coupling reactions. Our facility produces this intermediate under stringent quality management systems to ensure consistency and reliability for downstream chemical processes. As a key precursor, it facilitates the construction of complex molecular architectures required in the fine chemicals sector.

Chemical Properties and Specifications

The molecular structure of 4-Bromoveratrole includes two methoxy groups that activate the aromatic ring, enhancing its reactivity in electrophilic substitution reactions. The bromine substituent provides a handle for palladium-catalyzed cross-coupling reactions, such as Suzuki or Heck couplings. We maintain high industrial purity standards to minimize side reactions during synthesis. The physical state is a colorless transparent liquid, which simplifies handling and dosing in reactor systems. Below are the detailed technical specifications for our standard grade:

ParameterValue
CAS Number2859-78-1
Molecular FormulaC8H9BrO2
Molecular Weight217.060 g/mol
AppearanceColorless transparent liquid
Assay (Purity)≥98.0%
Density1.4±0.1 g/cm3
Boiling Point255.5±0.0 °C at 760 mmHg
Flash Point109.4±0.0 °C
Refractive Index1.528

Industrial Applications

This compound is primarily utilized as an intermediate in the synthesis of pharmaceuticals and agrochemicals. The electron-rich nature of the dimethoxybenzene ring allows for selective functionalization, making it invaluable for medicinal chemistry campaigns. Researchers and process chemists employ this material to develop active pharmaceutical ingredients (APIs) and specialized crop protection agents. Its stability and reactivity profile make it a preferred choice for multi-step synthesis routes where high fidelity is required. Additionally, it serves as a reference standard in analytical laboratories for quality assurance testing.

Quality Assurance and Storage

We adhere to rigorous quality control protocols throughout the manufacturing process. Each batch undergoes comprehensive analysis using gas chromatography and other spectroscopic methods to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment to document compliance with specifications. For optimal stability, 4-Bromoveratrole should be stored in a cool, ventilated area away from direct sunlight and incompatible materials. Containers must be kept tightly closed to prevent moisture absorption or contamination. We recommend using appropriate personal protective equipment during handling to ensure safety in the workplace. Our logistics team ensures secure packaging, typically in 200 kg drums, with customization available to meet specific client requirements.