4-Carboxy-3-fluorophenylboronic acid
- CAS No.120153-08-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Carboxy-3-fluorophenylboronic acid (CAS 120153-08-4) designed for pharmaceutical synthesis. Reliable supply with strict quality control for global research and production needs.
Request Bulk PricingProduct Technical Details
Product Overview
4-Carboxy-3-fluorophenylboronic acid is a specialized organic compound widely recognized for its utility in modern medicinal chemistry and organic synthesis. As a fluorinated boronic acid derivative, this molecule serves as a critical building block for the construction of complex pharmaceutical architectures. The presence of the fluorine atom enhances metabolic stability and bioavailability in downstream drug candidates, making this intermediate highly valuable for research and development teams focused on novel therapeutic agents.
Our manufacturing process ensures consistent quality and high purity levels, adhering to strict international standards. We understand the precision required in pharmaceutical synthesis, which is why every batch undergoes rigorous analytical testing before release. This commitment to quality makes our product a preferred choice for laboratories and production facilities worldwide.
Technical Specifications
The following table outlines the key physical and chemical properties of our 4-Carboxy-3-fluorophenylboronic acid. These parameters are verified through advanced chromatographic and spectroscopic methods to guarantee reliability.
| Parameter | Specification |
|---|---|
| CAS Number | 120153-08-4 |
| Molecular Formula | C7H6BFO4 |
| Molecular Weight | 183.93 g/mol |
| Appearance | White powder |
| Assay (Purity) | ≥98.0% |
| Water Content | ≤0.50% |
| Melting Point | 236-240°C |
| Density | 1.49 g/cm3 |
Industrial Applications
This compound is primarily utilized as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its structural features allow it to participate effectively in palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling. This reaction type is fundamental in forming carbon-carbon bonds, enabling chemists to assemble complex biaryl structures found in many modern medications.
Key advantages for process chemists include:
- High reactivity in cross-coupling conditions.
- Enhanced stability due to fluorine substitution.
- Compatible with various solvent systems used in industrial scale-up.
- Consistent batch-to-batch reproducibility for manufacturing.
Quality Assurance and Packaging
We prioritize safety and integrity throughout the supply chain. The product is classified as non-dangerous goods for transport, simplifying logistics and reducing shipping costs. Each drum is sealed to prevent moisture absorption, ensuring the chemical stability of the boronic acid moiety during storage.
Standard packaging is available in 25kg drums, though we offer flexible customization to meet specific client requirements. Comprehensive documentation, including Certificates of Analysis (COA), Method of Analysis (MOA), and Safety Data Sheets (SDS), is provided with every shipment. Our global distribution network ensures timely delivery to support your production schedules without interruption.
