4-Chloro-1-benzothiophene
- CAS No.66490-33-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 4-Chloro-1-benzothiophene (CAS 66490-33-3) designed for pharmaceutical synthesis. Reliable supply for API manufacturing with strict quality control.
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Product Overview
4-Chloro-1-benzothiophene is a specialized heterocyclic organic compound that serves as a critical building block in modern pharmaceutical chemistry. Characterized by its benzothiophene scaffold with a chloro substitution at the fourth position, this chemical exhibits unique reactivity profiles suitable for various cross-coupling reactions. Our manufacturing process ensures consistent quality, making it an ideal candidate for complex organic synthesis pathways required in the development of advanced therapeutic agents.
As a leading global manufacturer, we understand the stringent requirements of the pharmaceutical industry. This product is synthesized under controlled conditions to minimize impurities and maximize yield. The presence of the chlorine atom allows for versatile functionalization, enabling chemists to construct more complex molecular architectures efficiently. Whether used in research and development or scaled for industrial production, our material meets the highest standards of reliability.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 4-Chloro-1-benzothiophene |
| CAS Number | 66490-33-3 |
| Molecular Formula | C8H5ClS |
| Molecular Weight | 168.64 g/mol |
| Purity | ≥98.0% |
| Appearance | White solid or light yellow liquid |
| Boiling Point | 261.5±13.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 147.6±6.5 °C |
Industrial Applications
This compound is primarily utilized as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Notably, it plays a significant role in the production pathways for neurological therapeutics and antipsychotic medications. The robust nature of the benzothiophene ring system provides stability during multi-step synthesis, while the chloro group offers a convenient handle for palladium-catalyzed coupling reactions such as Suzuki or Buchwald-Hartwig transformations.
Beyond pharmaceuticals, this chemical finds utility in the development of specialized organic materials. Its electronic properties make it suitable for research into organic semiconductors and functional materials. Our clients value this product for its consistency, which reduces variability in downstream processes and ensures reproducible results in final product formulations.
Quality Assurance and Storage
Quality is the cornerstone of our operation. Every batch of 4-Chloro-1-benzothiophene undergoes rigorous testing using advanced analytical techniques including HPLC and GC-MS. We provide a comprehensive Certificate of Analysis (COA) with every shipment, detailing purity levels and physical properties. This transparency allows our partners to maintain their own quality standards without compromise.
- Strict quality control protocols at every production stage.
- Comprehensive documentation including COA and MSDS.
- Flexible packaging options to suit laboratory or industrial needs.
- Global logistics support ensuring timely and safe delivery.
Proper storage is essential to maintain the integrity of the chemical. The product should be stored in a cool and dry well-closed container. It is imperative to keep the material away from moisture and strong light or heat sources to prevent degradation. When handled according to safety guidelines, this intermediate remains stable for extended periods, ensuring long-term usability for your projects.
