Intermediates

4-Chloro-2,3-Dimethylpyridine 1-Oxide

  • CAS No.59886-90-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade 4-Chloro-2,3-Dimethylpyridine 1-Oxide designed for pharmaceutical synthesis. Available in bulk with full documentation.

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Product Technical Details

Product Overview

4-Chloro-2,3-Dimethylpyridine 1-Oxide is a highly specialized heterocyclic compound serving as a critical building block in modern pharmaceutical manufacturing. As a key pyridine N-oxide derivative, this chemical intermediate is engineered to meet the rigorous demands of complex organic synthesis pathways. Our facility produces this compound under strict quality control protocols to ensure consistent molecular integrity and high purity levels suitable for downstream drug substance production.

This material is particularly valued in the synthesis of proton pump inhibitors, acting as a essential precursor in the construction of advanced therapeutic molecules. We understand the importance of supply chain reliability in the pharmaceutical sector, which is why we maintain robust inventory levels and streamlined logistics to support global research and production needs.

Technical Specifications

ParameterSpecification
CAS Number59886-90-7
Molecular FormulaC7H8ClNO
Molecular Weight157.598 g/mol
AppearanceOff-white to light yellow crystalline powder
Assay (HPLC)≥98.0%
Moisture Content≤0.5%
Melting Point103-105°C
Boiling Point338.5±37.0 °C at 760 mmHg
Density1.2±0.1 g/cm3

Industrial Applications

The primary application of 4-Chloro-2,3-Dimethylpyridine 1-Oxide lies within the pharmaceutical intermediate sector. It serves as a vital structural component in the manufacturing process of specific gastrointestinal therapeutics. The unique reactivity of the N-oxide functional group allows for selective transformations that are difficult to achieve with standard pyridine derivatives.

  • Key intermediate for the synthesis of Rabeprazole and related analogs.
  • Utilized in heterocyclic chemistry for developing novel drug candidates.
  • Employed in research and development for structure-activity relationship studies.
  • Suitable for scale-up processes requiring high chemical stability.

Quality Assurance and Logistics

Quality is the cornerstone of our manufacturing philosophy. Every batch of 4-Chloro-2,3-Dimethylpyridine 1-Oxide undergoes comprehensive analytical testing using high-performance liquid chromatography and other validated methods. We provide a complete Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with international chemical safety standards.

For storage, we recommend keeping the product in a cool, ventilated environment away from direct sunlight and moisture to maintain stability. Our standard packaging consists of 25 kg drums, though we offer flexible customization options to suit specific client requirements. As a global manufacturer, we are committed to delivering bulk quantities with competitive pricing and reliable lead times.