Intermediates

4-Chloro-2,5-difluorobenzaldehyde

  • CAS No.879093-02-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 4-Chloro-2,5-difluorobenzaldehyde intermediate for pharmaceutical research and organic synthesis. Available in bulk with comprehensive QC documentation.

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Product Technical Details

Product Overview

4-Chloro-2,5-difluorobenzaldehyde is a highly specialized fluorinated aromatic compound designed for advanced pharmaceutical research and organic synthesis applications. As a critical building block in medicinal chemistry, this substance features a unique substitution pattern with chlorine and fluorine atoms on the benzaldehyde core, offering enhanced metabolic stability and binding affinity in downstream drug discovery processes. Our manufacturing facility ensures that every batch meets rigorous international standards for purity and consistency, making it an ideal choice for laboratories and industrial-scale synthesis operations.

The strategic placement of halogen substituents allows chemists to explore diverse chemical transformations, particularly in the development of neurological therapeutics. This compound serves as a key precursor in the synthesis of complex molecular structures, including quinuclidine amide derivatives. By utilizing high-grade raw materials and optimized production protocols, we deliver a product that supports reliable experimental outcomes and scalable manufacturing workflows.

Technical Specifications

ParameterValue
Chemical Name4-Chloro-2,5-difluorobenzaldehyde
CAS Number879093-02-4
Molecular FormulaC7H3ClF2O
Molecular Weight176.55 g/mol
AppearanceWhite powder
Purity≥99.0%
Density1.453 g/cm3
Boiling Point212.3 °C
Flash Point82.2 °C
Refractive Index1.536

Industrial Applications

This fluorinated benzaldehyde derivative is primarily utilized in the pharmaceutical industry for the construction of active pharmaceutical ingredients (APIs) and research compounds. Its primary application involves serving as a reactant in the synthesis of quinuclidine amide compounds, which are investigated for their potential as pharmacologically acceptable salts. These downstream products are often studied in the context of alpha-7 nicotinic acetylcholine receptor agonists, contributing to broader research into neurological therapeutics and cognitive disorder treatments.

Beyond specific receptor targeting, the compound's reactivity makes it suitable for various organic synthesis routes requiring electrophilic aromatic substitution or condensation reactions. The high purity level ensures minimal side reactions during complex multi-step synthesis, thereby improving overall yield and reducing purification burdens. Researchers value this intermediate for its stability under standard laboratory conditions and its compatibility with diverse catalytic systems.

Quality Assurance and Storage

We maintain a strict quality control framework to guarantee the integrity of 4-Chloro-2,5-difluorobenzaldehyde from production to delivery. Each batch is accompanied by a Certificate of Analysis (COA) verifying physical and chemical properties against specified limits. Our commitment to quality assurance includes regular testing for impurities, moisture content, and structural confirmation using advanced spectroscopic methods.

  • Packaging: Standard 25 kg drums, with custom packaging options available upon request to suit specific logistical needs.
  • Storage: Store in a cool, ventilated place away from direct sunlight and moisture to maintain stability.
  • Safety: Handle with appropriate personal protective equipment and follow standard chemical safety protocols.
  • Supply: Reliable global manufacturing capacity ensures consistent supply for long-term projects.

For detailed technical data sheets or bulk pricing inquiries, please contact our sales team. We are dedicated to supporting your research and production goals with premium chemical intermediates.